小鼠中间重复DNA元件新家族（LTR-IS）移动性的证据。
Evidence for mobility of a new family of mouse middle repetitive DNA elements (LTR-IS).
作者信息
Wirth T, Schmidt M, Baumruker T, Horak I
出版信息
Nucleic Acids Res. 1984 Apr 25;12(8):3603-10. doi: 10.1093/nar/12.8.3603.
Locus variation and sequence conservation of mouse LTR-IS elements, a new family of middle repetitive DNA sequences was studied. It is shown that LTR-IS sequences are present in all the inbred strains and subspecies of M. musculus tested and in M. cooki and M. caroli. Their arrangement in mouse genomes is polymorphic. Southern blot analysis and DNA sequencing revealed the existence of homologous DNA sequences with and without LTR-IS element insertion. LTR-IS sequences therefore appear to have arisen in early mouse ancestors and have, at least at some point, been mobile.
研究了小鼠LTR - IS元件（一种新的中等重复DNA序列家族）的基因座变异和序列保守性。结果表明，LTR - IS序列存在于所有测试的小家鼠近交系和亚种以及库克小家鼠和卡罗小家鼠中。它们在小鼠基因组中的排列是多态性的。Southern印迹分析和DNA测序揭示了存在有和没有LTR - IS元件插入的同源DNA序列。因此，LTR - IS序列似乎在早期小鼠祖先中就已出现，并且至少在某些时候是可移动的。
Zotero 插件