Biggar R J, Andersen H K, Ebbesen P, Melbye M, Goedert J J, Mann D L, Strong D M
Br Med J (Clin Res Ed). 1983 Jun 25;286(6383):2010-2. doi: 10.1136/bmj.286.6383.2010.
Seminal fluid samples from 84 Danish homosexual men were successfully cultured to determine the prevalence of cytomegalovirus excretion. Ten (15%) out of 66 men positive for the antibody were found to be excreting the virus. Although the proportion excreting was inversely related to age (p less than 0.01), three men aged over 30 and with many years of homosexual experience excreted the virus. In addition, a 50 year old man with Kaposi's sarcoma excreted the virus. A further study of the ratio of T cell helpers to suppressors in the men aged over 30 and a series of age matched non-excreting homosexual control or heterosexual men showed that those excreting cytomegalovirus in their seminal fluid had statistically lower ratios (all less than 0.77) than the controls (p less than 0.05). Excretion of cytomegalovirus may be related to re-emergence of latent infection in immunosuppressed homosexual men.
对84名丹麦同性恋男性的精液样本进行了成功培养，以确定巨细胞病毒排泄的患病率。在66名抗体呈阳性的男性中，有10名（15%）被发现正在排泄该病毒。虽然排泄病毒的比例与年龄呈负相关（p小于0.01），但有3名年龄超过30岁且有多年同性恋经历的男性排泄了该病毒。此外，一名患有卡波西肉瘤的50岁男性也排泄了该病毒。对30岁以上男性以及一系列年龄匹配的未排泄病毒的同性恋对照或异性恋男性的辅助性T细胞与抑制性T细胞比例进行的进一步研究表明，精液中排泄巨细胞病毒的男性其比例在统计学上低于对照组（均小于0.77）（p小于0.05）。巨细胞病毒的排泄可能与免疫抑制的同性恋男性中潜伏感染的重新出现有关。
