Coutinho R A, Albrecht-van Lent P, Lelie N, Nagelkerke N, Kuipers H, Rijsdijk T
Br Med J (Clin Res Ed). 1983 Dec 10;287(6407):1743-5. doi: 10.1136/bmj.287.6407.1743.
In a study of 689 male homosexuals 290 (42%) were found to have antibodies to hepatitis A virus. The 399 men who did not have antibodies were followed up for up to 690 days, and 35 cases of hepatitis A were detected. The attack rate at the end of the study was 14%. The incidence climbed steadily, indicating that the cases of hepatitis A did not occur in clusters. Statistical analysis showed that the prevalence of antibodies to hepatitis A virus was significantly correlated with the duration of homosexual activity (p less than 0.006), and this was independent of age. The incidence of hepatitis A was found to be correlated with the number of different sexual partners in the preceding six months. It is concluded that hepatitis A is a sexually transmitted disease among homosexual men in countries with a low rate of exposure to hepatitis A during childhood.
在一项对689名男性同性恋者的研究中，发现290人（42%）有甲型肝炎病毒抗体。对399名没有抗体的男性进行了长达690天的随访，检测到35例甲型肝炎病例。研究结束时的发病率为14%。发病率稳步上升，表明甲型肝炎病例并非聚集发生。统计分析表明，甲型肝炎病毒抗体的流行率与同性恋活动的持续时间显著相关（p小于0.006），且与年龄无关。发现甲型肝炎的发病率与前六个月不同性伴侣的数量相关。得出的结论是，在儿童时期甲型肝炎暴露率较低的国家，甲型肝炎是男性同性恋者中的一种性传播疾病。
