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The possible relation of glutathione, melanin and 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP) to Parkinson's disease.

作者信息

Bannon M J, Goedert M, Williams B

出版信息

Biochem Pharmacol. 1984 Sep 1;33(17):2697-8. doi: 10.1016/0006-2952(84)90682-8.

DOI:10.1016/0006-2952(84)90682-8
PMID:6331828
Abstract
摘要

相似文献

1
The possible relation of glutathione, melanin and 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP) to Parkinson's disease.谷胱甘肽、黑色素与1-甲基-4-苯基-1,2,5,6-四氢吡啶（MPTP）与帕金森病的可能关系。
Biochem Pharmacol. 1984 Sep 1;33(17):2697-8. doi: 10.1016/0006-2952(84)90682-8.
2
Mechanisms underlying neuronal degeneration in Parkinson's disease: an experimental and theoretical treatise.帕金森病神经元变性的潜在机制：一项实验与理论专著。
Mov Disord. 1989;4 Suppl 1:S15-25. doi: 10.1002/mds.870040504.
3
Neuromelanin and its possible protective and destructive properties.神经黑色素及其可能的保护和破坏特性。
Pigment Cell Res. 1987;1(3):133-6. doi: 10.1111/j.1600-0749.1987.tb00403.x.
4
Development of new pharmacological approaches in Parkinson's disease.帕金森病新药理学方法的发展
Adv Neurol. 1987;45:513-8.
5
[Significance of the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine for the etiology and therapy of idiopathic Parkinson disease].[神经毒素1-甲基-4-苯基-1,2,3,6-四氢吡啶在特发性帕金森病病因学及治疗中的意义]
Fortschr Neurol Psychiatr. 1989 Apr;57(4):142-8. doi: 10.1055/s-2007-1000755.
6
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) induced dopamine D2 receptor hypersensitivity in the mouse is transient.1-甲基-4-苯基-1,2,3,6-四氢吡啶（MPTP）诱导的小鼠多巴胺D2受体超敏反应是短暂的。
Res Commun Chem Pathol Pharmacol. 1985 May;48(2):163-71.
7
Parkinson's disease: current view.帕金森病：当前观点
Am Fam Physician. 1987 Mar;35(3):201-6.
8
Evidence for neuromelanin involvement in MPTP-induced neurotoxicity.神经黑色素参与1-甲基-4-苯基-1,2,3,6-四氢吡啶（MPTP）诱导的神经毒性的证据。
Nature. 1987;327(6120):324-6. doi: 10.1038/327324a0.
9
Cocaine blocks the dopamine depletion induced by MPTP.可卡因可阻断由1-甲基-4-苯基-1,2,3,6-四氢吡啶（MPTP）诱导的多巴胺耗竭。
Res Commun Chem Pathol Pharmacol. 1985 Jul;49(1):145-8.
10
Autoradiographic distributions of neurotransmitter receptors in the human brains of Parkinson's disease and primate models of MPTP-induced parkinsonism.
Adv Neurol. 1987;45:159-65.

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1
Glutathione in Brain Disorders and Aging.脑疾病和衰老中的谷胱甘肽。
Molecules. 2022 Jan 5;27(1):324. doi: 10.3390/molecules27010324.
2
Association Between Glutathione Peroxidase-1 (GPx-1) Polymorphisms and Schizophrenia in the Chinese Han Population.中国汉族人群中谷胱甘肽过氧化物酶-1（GPx-1）基因多态性与精神分裂症的关联
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3
Association between GPx-1 polymorphisms and personality traits in healthy Chinese-Han subjects.中国汉族健康人群中 GPx-1 多态性与人格特质的关联。
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Pre-clinical therapeutic development of a series of metalloporphyrins for Parkinson's disease.一系列用于帕金森病的金属卟啉的临床前治疗开发
Toxicol Appl Pharmacol. 2017 Jul 1;326:34-42. doi: 10.1016/j.taap.2017.04.004. Epub 2017 Apr 8.
5
A disruption in iron-sulfur center biogenesis via inhibition of mitochondrial dithiol glutaredoxin 2 may contribute to mitochondrial and cellular iron dysregulation in mammalian glutathione-depleted dopaminergic cells: implications for Parkinson's disease.通过抑制线粒体二硫键谷胱甘肽还原酶 2 导致铁硫中心生物发生中断，可能导致哺乳动物谷胱甘肽耗竭的多巴胺能细胞中线粒体和细胞内铁的失调：对帕金森病的影响。
Antioxid Redox Signal. 2009 Sep;11(9):2083-94. doi: 10.1089/ars.2009.2489.
6
Inducible alterations of glutathione levels in adult dopaminergic midbrain neurons result in nigrostriatal degeneration.成年多巴胺能中脑神经元中谷胱甘肽水平的诱导性改变会导致黑质纹状体变性。
J Neurosci. 2007 Dec 19;27(51):13997-4006. doi: 10.1523/JNEUROSCI.3885-07.2007.
7
An orally active catalytic metalloporphyrin protects against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity in vivo.一种口服活性催化金属卟啉可在体内预防1-甲基-4-苯基-1,2,3,6-四氢吡啶神经毒性。
J Neurosci. 2007 Apr 18;27(16):4326-33. doi: 10.1523/JNEUROSCI.0019-07.2007.
8
Modulation of [3H]dopamine release by glutathione in mouse striatal slices.谷胱甘肽对小鼠纹状体切片中[3H]多巴胺释放的调节作用。
Neurochem Res. 2007 Aug;32(8):1357-64. doi: 10.1007/s11064-007-9315-z. Epub 2007 Mar 31.
9
Neuroprotective effects of alpha-dihydroergocryptine against damages in the substantia nigra caused by severe treatment with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Acta Neuropathol. 1993;85(4):404-13. doi: 10.1007/BF00334452.
10
MPTP parkinsonism.1-甲基-4-苯基-1,2,3,6-四氢吡啶所致帕金森综合征
Br Med J (Clin Res Ed). 1984 Nov 24;289(6456):1401-2. doi: 10.1136/bmj.289.6456.1401.