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MPTP parkinsonism.

作者信息

Williams A

出版信息

Br Med J (Clin Res Ed). 1984 Nov 24;289(6456):1401-2. doi: 10.1136/bmj.289.6456.1401.

DOI:10.1136/bmj.289.6456.1401
PMID:6437573
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1443637/
Abstract
摘要

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本文引用的文献

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The neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in the monkey and man.1-甲基-4-苯基-1,2,3,6-四氢吡啶对猴和人的神经毒性
Can J Neurol Sci. 1984 Feb;11(1 Suppl):166-8. doi: 10.1017/s0317167100046345.
2
Parkinsonism induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP): implications for treatment and the pathogenesis of Parkinson's disease.1-甲基-4-苯基-1,2,3,6-四氢吡啶（MPTP）诱发的帕金森综合征：对帕金森病治疗及发病机制的启示
Can J Neurol Sci. 1984 Feb;11(1 Suppl):160-5. doi: 10.1017/s0317167100046333.
3
Selective nigral toxicity after systemic administration of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyrine (MPTP) in the squirrel monkey.松鼠猴全身给予1-甲基-4-苯基-1,2,5,6-四氢吡啶（MPTP）后的选择性黑质毒性
Brain Res. 1984 Feb 6;292(2):390-4. doi: 10.1016/0006-8993(84)90777-7.
4
Parkinson's disease in a chemist working with 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine.
N Engl J Med. 1983 Aug 4;309(5):310. doi: 10.1056/nejm198308043090511.
5
Protection against the dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine by monoamine oxidase inhibitors.单胺氧化酶抑制剂对1-甲基-4-苯基-1,2,5,6-四氢吡啶多巴胺能神经毒性的保护作用。
Nature. 1984;311(5985):467-9. doi: 10.1038/311467a0.
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Intraneuronal generation of a pyridinium metabolite may cause drug-induced parkinsonism.神经元内吡啶代谢物的生成可能导致药物性帕金森综合征。
Nature. 1984;311(5985):464-7. doi: 10.1038/311464a0.
7
The possible relation of glutathione, melanin and 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP) to Parkinson's disease.谷胱甘肽、黑色素与1-甲基-4-苯基-1,2,5,6-四氢吡啶（MPTP）与帕金森病的可能关系。
Biochem Pharmacol. 1984 Sep 1;33(17):2697-8. doi: 10.1016/0006-2952(84)90682-8.
8
A primate model of parkinsonism: selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.帕金森病的灵长类动物模型：N-甲基-4-苯基-1,2,3,6-四氢吡啶对黑质致密部多巴胺能神经元的选择性破坏。
Proc Natl Acad Sci U S A. 1983 Jul;80(14):4546-50. doi: 10.1073/pnas.80.14.4546.
9
Aetiology of Parkinson's disease.帕金森病的病因
Lancet. 1983;2(8365-66):1457-9. doi: 10.1016/s0140-6736(83)90802-4.
10
Inhibition of biogenic amine uptake by hydrogen peroxide: a mechanism for toxic effects of 6-hydroxydopamine.过氧化氢对生物胺摄取的抑制作用：6-羟基多巴胺毒性作用的一种机制。
Science. 1971 Jun 18;172(3989):1257-8. doi: 10.1126/science.172.3989.1257.