Amarnath V, Miller T L, Broom A D
Biochim Biophys Acta. 1984 Aug 21;800(3):207-13. doi: 10.1016/0304-4165(84)90397-0.
The synthesis of a high-molecular-weight, putatively all-syn DNA analogue, poly(8-bromo-2'-deoxyadenylic acid), is described. The syn----anti transition was shown to be both salt and temperature dependent. Conditions were found which favored 'normal' Watson-Crick pairing and duplex formation with poly(dT).
本文描述了一种高分子量、假定全为顺式的DNA类似物聚(8-溴-2'-脱氧腺苷酸)的合成。结果表明,顺式-反式转变既依赖于盐,也依赖于温度。已发现有利于与聚(dT)形成“正常”沃森-克里克配对和双链体的条件。