Brener B J, Brief D K, Alpert J, Goldenkranz R J, Parsonnet V, Feldman S, Gielchinsky I, Abel R M, Hochberg M, Hussain M
J Vasc Surg. 1984 Mar;1(2):326-38.
From January 1979 through December 1982, 2026 patients scheduled to undergo open heart surgery were evaluated by a preoperative battery of noninvasive carotid tests including phonoangiography, oculopneumoplethysmography, pulse-timing oculoplethysmography, periorbital Doppler examination, and during the last 12 months, continuous-wave Doppler ultrasonography with spectral analysis. The incidence of hemispheric neurologic deficit following cardiac surgery in the 47 patients with carotid disease was 14.9%; the incidence in patients with no carotid disease was 1.9% (p less than 0.001). Fourteen of the 47 patients were not candidates for carotid surgery because of unilateral occlusion in 13 and bilateral occlusion in one. Three of the 14 (21.4%) had intraoperative strokes on the appropriate side. Thirty-three of the 47 had operable carotid disease. Four with unilateral stenosis had no carotid surgery; one had a postoperative deficit on the side referable to the nonstenotic artery. Eighteen with unilateral stenosis underwent simultaneous cardiac and carotid surgery; one (5.6%) had a transient deficit. Seven patients with bilateral stenosis underwent cardiac and unilateral carotid surgery; no deficits occurred. Four patients with unilateral stenosis and contralateral occlusion underwent combined surgery; one had a transient ischemic attack and one a fatal stroke, both referable to the hemisphere ipsilateral to the occlusion. It appears that the presence of carotid disease increased the risk of stroke during heart surgery. Proof that carotid endarterectomy lowers this risk awaits a prospective randomized trial.
从1979年1月至1982年12月,对2026例计划接受心脏直视手术的患者进行了术前一系列无创颈动脉检查评估,包括血管音图检查、眼体积描记法、脉搏定时眼体积描记法、眶周多普勒检查,在最后12个月期间还进行了带频谱分析的连续波多普勒超声检查。47例患有颈动脉疾病的患者心脏手术后半球神经功能缺损的发生率为14.9%;无颈动脉疾病患者的发生率为1.9%(P<0.001)。47例患者中有14例因13例单侧闭塞和1例双侧闭塞而不适合进行颈动脉手术。这14例患者中有3例(21.4%)在相应一侧发生术中中风。47例中有33例患有可手术治疗的颈动脉疾病。4例单侧狭窄患者未进行颈动脉手术;1例在非狭窄动脉一侧出现术后功能缺损。18例单侧狭窄患者同时进行了心脏和颈动脉手术;1例(5.6%)出现短暂性功能缺损。7例双侧狭窄患者进行了心脏和单侧颈动脉手术;未出现功能缺损。4例单侧狭窄且对侧闭塞患者进行了联合手术;1例发生短暂性脑缺血发作,1例发生致命性中风,均与闭塞同侧的半球有关。看来颈动脉疾病的存在增加了心脏手术期间中风的风险。颈动脉内膜切除术降低这种风险的证据有待前瞻性随机试验来证实。