抗核抗组蛋白抗体的意义
[Significance of antinuclear anti-histone antibodies].
作者信息
Ferec C, Youinou P, Le Goff P, Miossec P, Morin J F, Pennec Y, Morin P P, Le Menn G
出版信息
Ann Med Interne (Paris). 1984;135(6):427-30.
The results of routine antihistone antibody (AHA) assay in a preliminary series of 189 sera are presented. There were 23 positive tests (systemic lupus erythematosus, 8 cases; drug induced SLE, 4 cases; rheumatoid arthritis 7 cases; and multiple sclerosis, 1 case; chronic active hepatitis, 1 case; systemic sclerosis, 1 case and primary biliary cirrhosis 1 case). The results of routine assay in 5 other patients groups are reported: 30 spontaneous SLE (9 positive AHA), 63 rheumatoid arthritis (2 positive AHA), 19 Sjögren syndrome (no AHA), 11 primary biliary cirrhosis (1 positive AHA) and 7 mixed connective tissue disease (no AHA).
本文呈现了对189份血清进行常规抗组蛋白抗体（AHA）检测的结果。其中有23份检测呈阳性（系统性红斑狼疮8例；药物性红斑狼疮4例；类风湿关节炎7例；多发性硬化症1例；慢性活动性肝炎1例；系统性硬化症1例；原发性胆汁性肝硬化1例）。还报告了其他5组患者的常规检测结果：30例自发性系统性红斑狼疮（9例AHA阳性）、63例类风湿关节炎（2例AHA阳性）、19例干燥综合征（无AHA阳性）、11例原发性胆汁性肝硬化（1例AHA阳性）以及7例混合性结缔组织病（无AHA阳性）。
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