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1
A unique sequence in murine leukemia virus long terminal repeat functions as a termination signal for transcription in Escherichia coli.鼠白血病病毒长末端重复序列中的一个独特序列可作为大肠杆菌中转录的终止信号。
J Virol. 1983 Jan;45(1):456-61. doi: 10.1128/JVI.45.1.456-461.1983.
2
Slipped DNA structures within the enhancer region of the Moloney murine leukemia virus.莫洛尼鼠白血病病毒增强子区域内的DNA滑动结构
Biochem Biophys Res Commun. 1988 Oct 14;156(1):417-23. doi: 10.1016/s0006-291x(88)80857-x.
3
The long terminal repeat of Moloney sarcoma provirus.莫洛尼肉瘤前病毒的长末端重复序列。
Cold Spring Harb Symp Quant Biol. 1981;45 Pt 2:699-705. doi: 10.1101/sqb.1981.045.01.087.
4
Identification of a RNA polymerase II initiation site in the long terminal repeat of Moloney murine leukemia viral DNA.莫洛尼鼠白血病病毒DNA长末端重复序列中RNA聚合酶II起始位点的鉴定。
Proc Natl Acad Sci U S A. 1981 Sep;78(9):5411-5. doi: 10.1073/pnas.78.9.5411.
5
Demonstration of biological activity and nucleotide sequence of an in vitro synthesized clone of the Moloney murine sarcoma virus mos gene.莫洛尼鼠肉瘤病毒mos基因体外合成克隆的生物学活性及核苷酸序列的证明
J Virol. 1982 May;42(2):538-46. doi: 10.1128/JVI.42.2.538-546.1982.
6
Structure of Moloney murine leukemia viral DNA: nucleotide sequence of the 5' long terminal repeat and adjacent cellular sequences.莫洛尼鼠白血病病毒DNA的结构：5' 长末端重复序列及相邻细胞序列的核苷酸序列
Proc Natl Acad Sci U S A. 1980 Jun;77(6):3307-11. doi: 10.1073/pnas.77.6.3307.
7
Characterization of enhancer elements in the long terminal repeat of Moloney murine sarcoma virus.莫洛尼鼠肉瘤病毒长末端重复序列中增强子元件的特性分析。
J Virol. 1984 Jan;49(1):183-9. doi: 10.1128/JVI.49.1.183-189.1984.
8
Important role of the long terminal repeat of the helper Moloney murine leukemia virus in Abelson virus-induced lymphoma.莫洛尼氏鼠白血病辅助病毒长末端重复序列在阿贝尔森病毒诱导的淋巴瘤中的重要作用。
J Virol. 1987 Oct;61(10):3266-75. doi: 10.1128/JVI.61.10.3266-3275.1987.
9
Generation of glucocorticoid-responsive Moloney murine leukemia virus by insertion of regulatory sequences from murine mammary tumor virus into the long terminal repeat.通过将小鼠乳腺肿瘤病毒的调控序列插入长末端重复序列来产生糖皮质激素反应性莫洛尼鼠白血病病毒。
J Virol. 1985 Apr;54(1):133-44. doi: 10.1128/JVI.54.1.133-144.1985.
10
Evidence for a prokaryotic promoter in the murine mammary tumor virus long terminal repeat.鼠乳腺肿瘤病毒长末端重复序列中存在原核生物启动子的证据。
Gene. 1983 Aug;23(2):117-30. doi: 10.1016/0378-1119(83)90043-4.

引用本文的文献

1
Nucleotide sequence of the envelope gene of Gardner-Arnstein feline leukemia virus B reveals unique sequence homologies with a murine mink cell focus-forming virus.加德纳-阿恩斯坦猫白血病病毒B包膜基因的核苷酸序列显示出与鼠貂细胞集落形成病毒独特的序列同源性。
J Virol. 1983 Jun;46(3):871-80. doi: 10.1128/JVI.46.3.871-880.1983.
2
Molecular analysis and pathogenesis of the feline aplastic anemia retrovirus, feline leukemia virus C-Sarma.猫再生障碍性贫血逆转录病毒——猫白血病病毒C-Sarma的分子分析与发病机制
J Virol. 1986 Oct;60(1):242-50. doi: 10.1128/JVI.60.1.242-250.1986.
3
Generation of a uniform 3' end RNA of murine leukemia virus.鼠白血病病毒均匀3'端RNA的生成
J Virol. 1985 Jan;53(1):330-4. doi: 10.1128/JVI.53.1.330-334.1985.

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Transduction of linked genetic characters of the host by bacteriophage P1.噬菌体P1对宿主连锁遗传性状的转导
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Activation of the transforming potential of a normal cell sequence: a molecular model for oncogenesis.正常细胞序列转化潜能的激活：肿瘤发生的分子模型。
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Function of the retrovirus long terminal repeat.逆转录病毒长末端重复序列的功能。
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Cloning of avian tumor virus DNA fragments in plasmid pBR322: evidence for efficient transcription in E. coli from a virus-coded promoter.禽肿瘤病毒DNA片段在质粒pBR322中的克隆：来自病毒编码启动子的大肠杆菌高效转录证据
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Identification of a RNA polymerase II initiation site in the long terminal repeat of Moloney murine leukemia viral DNA.莫洛尼鼠白血病病毒DNA长末端重复序列中RNA聚合酶II起始位点的鉴定。
Proc Natl Acad Sci U S A. 1981 Sep;78(9):5411-5. doi: 10.1073/pnas.78.9.5411.
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Beta + thalassemia: aberrant splicing results from a single point mutation in an intron.β+地中海贫血：异常剪接由内含子中的单个点突变引起。
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Cloning and characterization of a transcription termination signal in bacteriophage lambda unresponsive to the N gene product.
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An avian tumor virus promoter directs expression of plasmid genes in Escherichia coli.一种禽肿瘤病毒启动子指导质粒基因在大肠杆菌中的表达。
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Long terminal repeat of murine retroviral DNAs: sequence analysis, host-proviral junctions, and preintegration site.小鼠逆转录病毒DNA的长末端重复序列：序列分析、宿主-病毒连接及整合前位点
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10
Plasmid vectors for positive selection of DNA inserts controlled by the lambda pL promoter, repressor and antitermination function.用于由λ pL启动子、阻遏物和抗终止功能控制的DNA插入片段阳性选择的质粒载体。
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鼠白血病病毒长末端重复序列中的一个独特序列可作为大肠杆菌中转录的终止信号。

A unique sequence in murine leukemia virus long terminal repeat functions as a termination signal for transcription in Escherichia coli.

作者信息

Honigman A, Panet A

出版信息

J Virol. 1983 Jan;45(1):456-61. doi: 10.1128/JVI.45.1.456-461.1983.

DOI:10.1128/JVI.45.1.456-461.1983
PMID:6337268
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC256430/
Abstract

Moloney murine leukemia virus DNA fragments were subcloned into two plasmids downstream of active promoters to detect termination sequences for transcription initiated at these promoters. Two of the viral DNA fragments (2,050 and 595 base pairs) were able to block transcription when inserted in one orientation but not when inserted in the other. These two viral DNA fragments contained long terminal repeat sequences. Deletion of 84 base pairs from the U-3 and R regions in the long terminal repeat removed the transcription termination activity.

摘要

莫洛尼鼠白血病病毒DNA片段被亚克隆到两个质粒中，位于活性启动子下游，以检测从这些启动子起始转录的终止序列。两个病毒DNA片段（2050和595个碱基对）以一种方向插入时能够阻断转录，但以另一种方向插入时则不能。这两个病毒DNA片段含有长末端重复序列。从长末端重复序列的U-3和R区域缺失84个碱基对消除了转录终止活性。