Lennerstrand G, Samuelsson B
Br J Ophthalmol. 1983 Mar;67(3):181-90. doi: 10.1136/bjo.67.3.181.
We have compared the effects on visual acuity and binocular functions of grating stimulation (CAM therapy) and full-time occlusion in 38 4-year-old, previously untreated amblyopic children. The patients were divided into subgroups with regard to amblyopia type and fixation pattern. We found that grating stimulation was slightly better than occlusion in improving visual acuity of anisometropic amblyopes with central fixation, but that both types of therapy were equally effective in strabismic amblyopia with central fixation and in amblyopia with eccentric fixation. However, maximal treatment effects were not reached with grating stimulation alone, as shown at follow-up after continued conventional therapy. Grating stimulation may be regarded as a valuable method at the initiation of treatment, particularly in anisometropic amblyopia, but it has to be supplemented with occlusion, which still must be regarded as the prime form of amblyopia therapy.
我们比较了光栅刺激疗法（CAM疗法）和全天遮盖疗法对38名4岁、此前未经治疗的弱视儿童视力及双眼视功能的影响。这些患者根据弱视类型和注视模式被分成了不同亚组。我们发现，对于中心注视的屈光参差性弱视患者，光栅刺激疗法在提高视力方面略优于遮盖疗法，但对于中心注视的斜视性弱视患者和偏心注视的弱视患者，这两种治疗方法的效果相当。然而，正如继续采用传统疗法后的随访结果所示，单独使用光栅刺激疗法并未达到最大治疗效果。光栅刺激疗法可被视为治疗起始阶段的一种有价值的方法，尤其是在屈光参差性弱视的治疗中，但必须辅以遮盖疗法，遮盖疗法仍应被视为弱视治疗的主要方式。
