美拉尼西亚椭圆形红细胞（卵形红细胞）在体外对诺氏疟原虫和恶性疟原虫入侵的抗性。
Resistance of Melanesian elliptocytes (ovalocytes) to invasion by Plasmodium knowlesi and Plasmodium falciparum malaria parasites in vitro.
作者信息
Hadley T, Saul A, Lamont G, Hudson D E, Miller L H, Kidson C
出版信息
J Clin Invest. 1983 Mar;71(3):780-2. doi: 10.1172/jci110827.
Abstract
Erythrocytes from humans with Melanesian elliptocytosis are resistant to invasion by Plasmodium falciparum in vitro and epidemiological evidence suggests they may be resistant to P. vivax and P. malariae. We have examined the ability of P. knowlesi merozoites to invade Melanesian elliptocytes in vitro as a definitive means of examining these cells for resistance to invasion by malarial species with different receptor requirements. The Melanesian elliptocytes were highly resistant to invasion by P. knowlesi merozoites showing that the resistance associated with this erythrocyte variant lies at a level common to the invasion pathway(s) of P. falciparum and P. knowlesi. This makes Melanesian elliptocytosis unique as no other human erythrocyte variant has been shown to be resistant to invasion by both species.
摘要
患有美拉尼西亚椭圆形红细胞增多症的人的红细胞在体外对恶性疟原虫的入侵具有抗性，流行病学证据表明它们可能对间日疟原虫和三日疟原虫也具有抗性。我们已经研究了诺氏疟原虫裂殖子在体外侵入美拉尼西亚椭圆形红细胞的能力，以此作为检测这些细胞对具有不同受体需求的疟原虫物种入侵抗性的决定性方法。美拉尼西亚椭圆形红细胞对诺氏疟原虫裂殖子的入侵具有高度抗性，这表明与这种红细胞变体相关的抗性存在于恶性疟原虫和诺氏疟原虫入侵途径的共同水平。这使得美拉尼西亚椭圆形红细胞增多症独一无二，因为没有其他人类红细胞变体被证明对这两种疟原虫的入侵都具有抗性。
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本文引用的文献
1
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Southeast Asian J Trop Med Public Health. 1981 Dec;12(4):549-55.
2
Erythrocytes deficiency in glycophorin resist invasion by the malarial parasite Plasmodium falciparum.缺乏血型糖蛋白的红细胞可抵抗疟原虫恶性疟原虫的入侵。
Nature. 1982 May 6;297(5861):64-6. doi: 10.1038/297064a0.
3
Ovalocytic erythrocytes from Melanesians are resistant to invasion by malaria parasites in culture.美拉尼西亚人的椭圆形红细胞在培养中对疟原虫的入侵具有抗性。
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4
Erythrocyte receptors for (Plasmodium knowlesi) malaria: Duffy blood group determinants.诺氏疟原虫疟疾的红细胞受体：达菲血型决定簇
Science. 1975 Aug 15;189(4202):561-3. doi: 10.1126/science.1145213.
5
Genetic factors and malaria in the Temuan.特穆安人的遗传因素与疟疾
Am J Hum Genet. 1976 Mar;28(2):179-88.
6
Erythrocyte receptors for malaria merozoites.疟原虫裂殖子的红细胞受体。
Am J Trop Med Hyg. 1977 Nov;26(6 Pt 2):204-8. doi: 10.4269/ajtmh.1977.26.204.
7
Selective depression of blood group antigens associated with hereditary ovalocytosis among melanesians.美拉尼西亚人中与遗传性椭圆形红细胞增多症相关的血型抗原的选择性抑制
Vox Sang. 1977;32(2):99-110. doi: 10.1111/j.1423-0410.1977.tb00612.x.
8
Genetics of red cells and susceptibility to malaria.红细胞遗传学与疟疾易感性
Blood. 1979 Nov;54(5):961-76.
9
Malaria and hereditary ovalocytosis.疟疾与遗传性椭圆形红细胞增多症。
Hum Genet. 1977 Jun 30;37(2):161-7. doi: 10.1007/BF00393579.
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J Exp Med. 1977 Jul 1;146(1):277-81. doi: 10.1084/jem.146.1.277.
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