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脂磷壁酸介导葡萄球菌对黏膜细胞的黏附。

Mediation of staphylococcal adherence to mucosal cells by lipoteichoic acid.

作者信息

Carruthers M M, Kabat W J

出版信息

Infect Immun. 1983 Apr;40(1):444-6. doi: 10.1128/iai.40.1.444-446.1983.

Abstract

Staphylococcal lipoteichoic acid markedly reduced adherence by Staphylococcus aureus to buccal cells in vitro, suggesting that lipoteichoic acid mediates adherence by that bacterium. Adherence inhibition by lipoteichoic acid was lost after deacylation of the preparation, suggesting that fatty acids on the molecule are essential to binding.

摘要

葡萄球菌脂磷壁酸在体外显著降低了金黄色葡萄球菌对颊细胞的黏附,这表明脂磷壁酸介导了该细菌的黏附。该制剂脱酰基后,脂磷壁酸的黏附抑制作用消失,这表明分子上的脂肪酸对结合至关重要。

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本文引用的文献

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Role of teichoic acid in the binding of Staphylococcus aureus to nasal epithelial cells.
J Infect Dis. 1980 Apr;141(4):463-5. doi: 10.1093/infdis/141.4.463.
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Bacterial cell surface amphiphiles.细菌细胞表面两亲分子。
Biochim Biophys Acta. 1980 May 27;604(1):1-26. doi: 10.1016/0005-2736(80)90583-0.
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Lipoteichoic acid and lipoteichoic acid carrier in Staphylococcus aureus H.
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