Kelly S L, Parry J M
Mutat Res. 1983 Mar;108(1-3):109-20. doi: 10.1016/0027-5107(83)90113-6.
Irradiation of yeast cultures with ultraviolet light at discrete stages during meiosis produces cyclic variations in sensitivity, i.e. cells are more sensitive to the lethal effects of UV light prior to entry into the meiotic DNA synthesis, and this corresponds to a peak of induction of point mutation. Cells become more resistant to both induced point mutation and lethality as they enter meiotic DNA synthesis, but become more sensitive again during spore formation. The induced level of intragenic recombination rises during the period of commitment to recombination to a level indistinguishable from the full meiotic level of spontaneous intragenic recombination. Induced reciprocal recombination remains above the spontaneous level up to the point of commitment to sporulation.
在减数分裂的不同阶段用紫外线照射酵母培养物会产生敏感性的周期性变化，即细胞在进入减数分裂DNA合成之前对紫外线的致死效应更敏感，这与点突变诱导的峰值相对应。当细胞进入减数分裂DNA合成时，它们对诱导的点突变和致死性都变得更具抗性，但在孢子形成过程中又变得更敏感。在承诺进行重组的时期内，基因内重组的诱导水平上升到与减数分裂自发基因内重组的完全水平无法区分的水平。诱导的相互重组在承诺形成孢子之前一直高于自发水平。
