Beardslee W R, Bemporad J, Keller M B, Klerman G L
Am J Psychiatry. 1983 Jul;140(7):825-32. doi: 10.1176/ajp.140.7.825.
The authors review published studies of the children of parents with major affective disorder and report the rates of diagnosable disorder in the children, their clinical symptoms and other behavioral disturbances, and the differing impact of parental illness at different ages and stages of development. There is significant risk to children in having parents with major affective disorder, and considerable impairment is evident in these children. The authors discuss the methodological issues in the studies and offer suggestions for future investigations.
作者回顾了已发表的关于患有重度情感障碍的父母的子女的研究，并报告了子女中可诊断疾病的发生率、他们的临床症状和其他行为障碍，以及父母疾病在不同年龄和发育阶段的不同影响。父母患有重度情感障碍会给子女带来重大风险，这些子女中明显存在相当程度的损害。作者讨论了这些研究中的方法学问题，并为未来的调查提出了建议。
