[双硫腙对胰岛素释放细胞的损伤作用]
[Damaging action of dithizone on insulin-releasing cells].
作者信息
Toroptsev I V, Eshchenko V A
出版信息
Biull Eksp Biol Med. 1983 Sep;96(9):23-5.
PMID:6351944
Abstract
Alterative action of dithizone was investigated in the experiments on various species of animals (fish, frogs, pigeons, mice, guinea pigs, golden hamsters, rats, rabbits, cats and dogs). The data received support the previously advanced suggestion that unsaturated (electrophilic) zinc complex formation is the basic mechanism of the alterative chelant's action.
摘要
在对各种动物（鱼、青蛙、鸽子、小鼠、豚鼠、金黄地鼠、大鼠、兔子、猫和狗）进行的实验中，研究了双硫腙的交替作用。所获得的数据支持了先前提出的建议，即不饱和（亲电）锌络合物的形成是交替螯合剂作用的基本机制。
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