Fogh-Andersen N, McNair P, Møller-Petersen J, Madsbad S
Scand J Clin Lab Invest Suppl. 1983;165:93-7.
The concentration of ionized calcium at pH 7.40, [Ca2+]7.4, in serum from 43 insulin dependent diabetic patients was lowered in comparison with 47 healthy controls (p less than 0.001), and the difference was biggest in children under sixteen. Serum total calcium, phosphate, and parathyroid hormone were normal, and it is inexplicable why the parathyroid glands did not react by raising serum total calcium. The lowered serum ionized calcium may contribute to the development of diabetic bone loss.
43名胰岛素依赖型糖尿病患者血清中pH值为7.40时的离子钙浓度[Ca2+]7.4，与47名健康对照者相比有所降低（p<0.001），且这种差异在16岁以下儿童中最为明显。血清总钙、磷酸盐和甲状旁腺激素均正常，目前尚无法解释甲状旁腺为何没有通过提高血清总钙来做出反应。血清离子钙降低可能会促使糖尿病性骨质流失的发生。
