Ganrot-Norlin K
Scand J Infect Dis. 1978;10(1):57-60. doi: 10.3109/inf.1978.10.issue-1.13.
IgG and albumin were determined in cerebrospinal fluid (CSF) and plasma by electroimmuno assay in 90 control patients. The curve for the ratios between concentration of IgG in CSF and in plasma versus the ratios between concentration of albumin in CSF and in plasma was practically linear (r=0.95). The scatter diagram of these ratios was used to investigate the occurrence of synthesis of IgG within the central nervous system in 55 cases of acute meningitis. No unmistakable intrathecal synthesis of IgG was demonstrated. No difference was found between the relative concentration of IgG in CSF early in the course of the disease and that observed later.
采用免疫电泳法对90例对照患者的脑脊液（CSF）和血浆中的IgG及白蛋白进行了测定。脑脊液中IgG浓度与血浆中IgG浓度之比，以及脑脊液中白蛋白浓度与血浆中白蛋白浓度之比的曲线实际上呈线性（r = 0.95）。利用这些比值的散点图对55例急性脑膜炎患者中枢神经系统内IgG合成情况进行了研究。未发现明确无误的鞘内IgG合成。在疾病早期脑脊液中IgG的相对浓度与后期观察到的相对浓度之间未发现差异。
