Odds F C, Abbott A B, Stiller R L, Scholer H J, Polak A, Stevens D A
J Clin Microbiol. 1983 Oct;18(4):849-57. doi: 10.1128/jcm.18.4.849-857.1983.
Strain phenotypes of 330 Candida albicans isolates from five areas in the United States were determined on the basis of nine biochemical tests. Statistical analysis of the distribution of phenotypes revealed no significant differences among types from different anatomical sources. However, there were some differences among the phenotypes of strains from the different geographical areas, and there were substantial differences in biochemical phenotypes associated with strains susceptible and resistant to 5-fluorocytosine and between strains of serotypes A and B. Geographical differences in phenotypes of C. albicans were also noted between the 330 U.S. isolates and 247 isolates from Britain. Cluster analysis of the U.S. strains alone and of all of the U.S. and U.K. strains showed that C. albicans phenotypes can be grouped into fewer than 20 clusters with common biochemical properties.
基于九项生化测试，确定了来自美国五个地区的330株白色念珠菌分离株的菌株表型。对表型分布的统计分析表明，来自不同解剖学来源的菌株类型之间没有显著差异。然而，来自不同地理区域的菌株表型存在一些差异，并且与对5-氟胞嘧啶敏感和耐药的菌株以及血清型A和B的菌株相关的生化表型存在实质性差异。在美国的330株分离株和来自英国的247株分离株之间也注意到白色念珠菌表型的地理差异。仅对美国菌株以及所有美国和英国菌株进行聚类分析表明，白色念珠菌表型可分为少于20个具有共同生化特性的聚类。
