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大肠杆菌的复制起始区域：核苷酸序列与功能单元

The replication origin region of Escherichia coli: nucleotide sequence and functional units.

作者信息

Buhk H J, Messer W

出版信息

Gene. 1983 Oct;24(2-3):265-79. doi: 10.1016/0378-1119(83)90087-2.

DOI:10.1016/0378-1119(83)90087-2
PMID:6357950
Abstract

The minichromosome pCM959 contains the DNA segment from bp -677 (left) to bp + 3335 (right) of the Escherichia coli replication origin, oriC. The nucleotide sequence of this plasmid was determined. The coding regions for proteins were identified, and the possible function of those proteins is discussed. Within oriC two extended systems of dyad symmetry were found, and their possible significance is considered.

摘要

微型染色体pCM959包含来自大肠杆菌复制起点oriC的从碱基对-677（左侧）到碱基对+3335（右侧）的DNA片段。测定了该质粒的核苷酸序列。鉴定了蛋白质的编码区，并讨论了这些蛋白质的可能功能。在oriC内发现了两个扩展的二重对称系统，并考虑了它们的可能意义。

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The replication origin region of Escherichia coli: nucleotide sequence and functional units.大肠杆菌的复制起始区域：核苷酸序列与功能单元
Gene. 1983 Oct;24(2-3):265-79. doi: 10.1016/0378-1119(83)90087-2.
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Functional analysis of minichromosome replication: bidirectional and unidirectional replication from the Escherichia coli replication origin, oriC.微型染色体复制的功能分析：来自大肠杆菌复制起点oriC的双向和单向复制
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The dnaA protein complex with the E. coli chromosomal replication origin (oriC) and other DNA sites.DnaA蛋白与大肠杆菌染色体复制起点（oriC）及其他DNA位点结合。
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Separation of the minimal replication region of the F plasmid into a replication origin segment and a trans-acting segment.F质粒最小复制区域分离为复制起始片段和反式作用片段。
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The 245 base-pair oriC sequence of the E. coli chromosome directs bidirectional replication at an adjacent region.大肠杆菌染色体的245个碱基对的oriC序列在相邻区域指导双向复制。
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Chromosomal replication origin from the marine bacterium Vibrio harveyi functions in Escherichia coli: oriC consensus sequence.来自海洋细菌哈维氏弧菌的染色体复制起点在大肠杆菌中发挥作用：oriC共有序列。
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Replication of M13 oriC bacteriophages in Escherichia coli rep mutant is dependent on the cloned Escherichia coli replication origin.M13 oriC噬菌体在大肠杆菌rep突变体中的复制依赖于克隆的大肠杆菌复制起点。
J Bacteriol. 1981 Feb;145(2):974-9. doi: 10.1128/jb.145.2.974-979.1981.

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A hybrid bacterial replication origin.一种混合细菌复制起点。
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Mechanism of origin unwinding: sequential binding of DnaA to double- and single-stranded DNA.复制起点解旋机制：DnaA蛋白与双链及单链DNA的顺序结合
EMBO J. 2001 Mar 15;20(6):1469-76. doi: 10.1093/emboj/20.6.1469.
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Microbiol Mol Biol Rev. 1998 Sep;62(3):814-984. doi: 10.1128/MMBR.62.3.814-984.1998.
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