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在孟加拉国农村的一项纵向研究中,营养不良是幼儿腹泻持续时间而非发病率的一个决定性因素。

Malnutrition is a determining factor in diarrheal duration, but not incidence, among young children in a longitudinal study in rural Bangladesh.

作者信息

Black R E, Brown K H, Becker S

出版信息

Am J Clin Nutr. 1984 Jan;39(1):87-94. doi: 10.1093/ajcn/39.1.87.

Abstract

Diarrhea and malnutrition are common in young children in developing countries and a reciprocal relationship has been postulated with diarrhea leading to malnutrition and malnutrition predisposing to diarrhea. To investigate the importance of malnutrition as a determining factor in diarrheal illnesses, data were analyzed from a longitudinal community-based study done in rural Bangladesh. Children classified by nutritional status according to a variety of anthropometric indicators were prospectively evaluated for incidence, duration, and etiology of diarrhea. Children with low weight for length had longer durations of diarrhea than better nourished children; however, children of differing nutritional status had similar diarrheal incidences. The duration of diarrhea, including that associated with enterotoxigenic Escherichia coli and Shigella, increased progressively as nutritional status indicators worsened. These results suggest that nutritional interventions alone are unlikely to reduce the high incidence of diarrhea, but that efforts to improve nutritional status may have a beneficial effect on the duration of diarrhea and its unfavorable nutritional consequences.

摘要

腹泻和营养不良在发展中国家的幼儿中很常见,并且存在一种相互关系,即腹泻导致营养不良,而营养不良又易引发腹泻。为了研究营养不良作为腹泻病决定因素的重要性,对在孟加拉国农村地区开展的一项基于社区的纵向研究数据进行了分析。根据各种人体测量指标对儿童的营养状况进行分类,并对腹泻的发病率、持续时间和病因进行前瞻性评估。身长体重低的儿童腹泻持续时间比营养状况较好的儿童更长;然而,不同营养状况的儿童腹泻发病率相似。随着营养状况指标变差,腹泻的持续时间,包括与产肠毒素大肠杆菌和志贺氏菌相关的腹泻持续时间,逐渐增加。这些结果表明,仅靠营养干预不太可能降低腹泻的高发病率,但改善营养状况的努力可能对腹泻持续时间及其不良营养后果产生有益影响。

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