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在核酸序列中定位信号的计算机方法。

Computer methods to locate signals in nucleic acid sequences.

作者信息

Staden R

出版信息

Nucleic Acids Res. 1984 Jan 11;12(1 Pt 2):505-19. doi: 10.1093/nar/12.1part2.505.

DOI:10.1093/nar/12.1part2.505
PMID:6364039
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC321067/
Abstract

This paper describes computer methods for locating signals in nucleic acid sequences. The signals include ribosome binding sites, promoter sequences and splice junctions. The methods are of use both to those trying to interpret the function of newly determined sequences and to those studying the molecular mechanisms involved in the recognition of these special signal sequences.

摘要

本文描述了在核酸序列中定位信号的计算机方法。这些信号包括核糖体结合位点、启动子序列和剪接位点。这些方法对于试图解读新确定序列功能的人以及研究识别这些特殊信号序列所涉及分子机制的人都有用处。

相似文献

1
Computer methods to locate signals in nucleic acid sequences.在核酸序列中定位信号的计算机方法。
Nucleic Acids Res. 1984 Jan 11;12(1 Pt 2):505-19. doi: 10.1093/nar/12.1part2.505.
2
Graphic methods to determine the function of nucleic acid sequences.用于确定核酸序列功能的图解方法。
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3
Construction of a general vector for efficient expression of mammalian proteins in bacteria: use of a synthetic ribosome binding site.用于在细菌中高效表达哺乳动物蛋白的通用载体构建：合成核糖体结合位点的应用。
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4
Measurements of the effects that coding for a protein has on a DNA sequence and their use for finding genes.蛋白质编码对DNA序列的影响的测量及其在寻找基因中的应用。
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6
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7
Ribosome biogenesis: role of small nucleolar RNA in maturation of eukaryotic rRNA.核糖体生物合成：小核仁RNA在真核生物核糖体RNA成熟中的作用
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本文引用的文献

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The ovalbumin gene family: structure of the X gene and evolution of duplicated split genes.卵清蛋白基因家族：X基因的结构与重复分裂基因的进化
Cell. 1980 Jul;20(3):625-37. doi: 10.1016/0092-8674(80)90309-8.
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A possible novel interaction between the 3'-end of 18 S ribosomal RNA and the 5'-leader sequence of many eukaryotic messenger RNAs.18 S核糖体RNA的3'端与许多真核生物信使RNA的5'前导序列之间可能存在一种新型相互作用。
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A catalogue of splice junction sequences.剪接连接序列目录。
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Use of the 'Perceptron' algorithm to distinguish translational initiation sites in E. coli.使用“感知器”算法区分大肠杆菌中的翻译起始位点。
Nucleic Acids Res. 1982 May 11;10(9):2997-3011. doi: 10.1093/nar/10.9.2997.
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The E. coli beta-lactamase attenuator mediates growth rate-dependent regulation.大肠杆菌β-内酰胺酶衰减子介导生长速率依赖性调控。
Nature. 1981 Mar 19;290(5803):221-5. doi: 10.1038/290221a0.
6
Characterization of promoter-cloning plasmids: analysis of operon structure in the rif region of Escherichia coli and isolation of an enhanced internal promoter mutant.启动子克隆质粒的特性分析：大肠杆菌rif区域操纵子结构的分析及增强型内部启动子突变体的分离
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Spacer mutations in the lac ps promoter.乳糖操纵子启动子中的间隔突变
Proc Natl Acad Sci U S A. 1982 Feb;79(4):1069-72. doi: 10.1073/pnas.79.4.1069.
8
Sequences of the recA gene and protein.recA基因和蛋白质的序列。
Proc Natl Acad Sci U S A. 1980 May;77(5):2611-5. doi: 10.1073/pnas.77.5.2611.
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Sequence determinants of promoter activity.启动子活性的序列决定因素。
Cell. 1982 Oct;30(3):843-53. doi: 10.1016/0092-8674(82)90289-6.
10
Promoter for the establishment of repressor synthesis in bacteriophage lambda.噬菌体λ中阻遏物合成建立的启动子。
Proc Natl Acad Sci U S A. 1980 Jun;77(6):3191-5. doi: 10.1073/pnas.77.6.3191.