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Nucleic Acids Res. 1984 Jan 11;12(1 Pt 2):551-67. doi: 10.1093/nar/12.1part2.551.
2
Graphic methods to determine the function of nucleic acid sequences.用于确定核酸序列功能的图解方法。
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Computer methods to locate signals in nucleic acid sequences.在核酸序列中定位信号的计算机方法。
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Correlation between the abundance of Escherichia coli transfer RNAs and the occurrence of the respective codons in its protein genes: a proposal for a synonymous codon choice that is optimal for the E. coli translational system.大肠杆菌转移RNA丰度与其蛋白质基因中相应密码子出现情况之间的相关性：关于一种对大肠杆菌翻译系统而言最优的同义密码子选择的提议。
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蛋白质编码对DNA序列的影响的测量及其在寻找基因中的应用。

Measurements of the effects that coding for a protein has on a DNA sequence and their use for finding genes.

作者信息

Staden R

出版信息

Nucleic Acids Res. 1984 Jan 11;12(1 Pt 2):551-67. doi: 10.1093/nar/12.1part2.551.

DOI:10.1093/nar/12.1part2.551
PMID:6364041
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC321070/
Abstract

Protein genes can be found either by searching the DNA sequence for signals such as ribosome binding sites or by looking for the effects that coding for a protein has on the coding sequence. This paper describes how these coding effects can be measured and used to detect protein coding regions.

摘要

蛋白质基因既可以通过在DNA序列中搜索诸如核糖体结合位点等信号来找到，也可以通过寻找编码蛋白质对编码序列产生的影响来找到。本文描述了如何测量这些编码效应并将其用于检测蛋白质编码区域。