Staden R
Nucleic Acids Res. 1984 Jan 11;12(1 Pt 2):551-67. doi: 10.1093/nar/12.1part2.551.
Protein genes can be found either by searching the DNA sequence for signals such as ribosome binding sites or by looking for the effects that coding for a protein has on the coding sequence. This paper describes how these coding effects can be measured and used to detect protein coding regions.
蛋白质基因既可以通过在DNA序列中搜索诸如核糖体结合位点等信号来找到,也可以通过寻找编码蛋白质对编码序列产生的影响来找到。本文描述了如何测量这些编码效应并将其用于检测蛋白质编码区域。