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1
Graphic methods to determine the function of nucleic acid sequences.用于确定核酸序列功能的图解方法。
Nucleic Acids Res. 1984 Jan 11;12(1 Pt 2):521-38. doi: 10.1093/nar/12.1part2.521.
2
Computer methods to locate signals in nucleic acid sequences.在核酸序列中定位信号的计算机方法。
Nucleic Acids Res. 1984 Jan 11;12(1 Pt 2):505-19. doi: 10.1093/nar/12.1part2.505.
3
Measurements of the effects that coding for a protein has on a DNA sequence and their use for finding genes.蛋白质编码对DNA序列的影响的测量及其在寻找基因中的应用。
Nucleic Acids Res. 1984 Jan 11;12(1 Pt 2):551-67. doi: 10.1093/nar/12.1part2.551.
4
A comprehensive sequence analysis program for the IBM personal computer.一款适用于IBM个人计算机的综合序列分析程序。
Nucleic Acids Res. 1984 Jan 11;12(1 Pt 2):581-99. doi: 10.1093/nar/12.1part2.581.
5
The codon preference plot: graphic analysis of protein coding sequences and prediction of gene expression.密码子偏好性图：蛋白质编码序列的图形分析及基因表达预测
Nucleic Acids Res. 1984 Jan 11;12(1 Pt 2):539-49. doi: 10.1093/nar/12.1part2.539.
6
A novel RNA product of the tyrT operon of Escherichia coli.大肠杆菌tyrT操纵子的一种新型RNA产物。
Nucleic Acids Res. 1991 Nov 11;19(21):5863-70. doi: 10.1093/nar/19.21.5863.
7
Closely spaced and divergent promoters for an aminoacyl-tRNA synthetase gene and a tRNA operon in Escherichia coli. Transcriptional and post-transcriptional regulation of gltX, valU and alaW.大肠杆菌中一个氨酰-tRNA合成酶基因和一个tRNA操纵子的紧密间隔且发散的启动子。gltX、valU和alaW的转录及转录后调控。
J Mol Biol. 1990 Aug 20;214(4):845-64. doi: 10.1016/0022-2836(90)90340-R.
8
PLASMAP: an interactive computational tool for storage, retrieval and device-independent graphic display of conventional restriction maps.PLASMAP：一种用于传统限制性图谱的存储、检索及与设备无关的图形显示的交互式计算工具。
Nucleic Acids Res. 1984 Jan 11;12(1 Pt 2):465-71. doi: 10.1093/nar/12.1part2.465.
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A computer program to search for tRNA genes.一个用于搜索转运RNA基因的计算机程序。
Nucleic Acids Res. 1980 Feb 25;8(4):817-25.
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Precise mapping and comparison of two evolutionarily related regions of the Escherichia coli K-12 chromosome. Evolution of valU and lysT from an ancestral tRNA operon.大肠杆菌K-12染色体两个进化相关区域的精确图谱绘制与比较。valU和lysT从一个祖先tRNA操纵子的进化。
J Mol Biol. 1990 Aug 20;214(4):825-43. doi: 10.1016/0022-2836(90)90339-N.

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Sequence of the nucleoprotein gene from a virulent British field isolate of transmissible gastroenteritis virus and its expression in Saccharomyces cerevisiae.来自英国一株强毒力传染性胃肠炎病毒野毒株的核蛋白基因序列及其在酿酒酵母中的表达
Mol Microbiol. 1988 Jan;2(1):89-99. doi: 10.1111/j.1365-2958.1988.tb00010.x.
2
Molecular cloning and analysis of four potato tuber mRNAs.马铃薯块茎 4 种 mRNA 的分子克隆与分析。
Plant Mol Biol. 1988 May;11(3):255-69. doi: 10.1007/BF00027383.
3
The agarase gene (dagA) of Streptomyces coelicolor A3(2): nucleotide sequence and transcriptional analysis.天蓝色链霉菌A3(2)的琼脂糖酶基因(dagA)：核苷酸序列及转录分析
Mol Gen Genet. 1987 Aug;209(1):101-9. doi: 10.1007/BF00329843.
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Characterization of cDNA for nodulin-75 of soybean: A gene product involved in early stages of root nodule development.大豆根瘤球蛋白 75 cDNA 的特性：一种参与根瘤发育早期阶段的基因产物。
Proc Natl Acad Sci U S A. 1987 Jul;84(13):4495-9. doi: 10.1073/pnas.84.13.4495.
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A sixth subunit of ATP synthase, an F(0) component, is encoded in the pea chloroplast genome.ATP 合酶的第六个亚基，即 F（0）成分，由豌豆叶绿体基因组编码。
EMBO J. 1986 Feb;5(2):217-22. doi: 10.1002/j.1460-2075.1986.tb04201.x.
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Sequencing of Escherichia coli O111 O-antigen gene cluster and identification of O111-specific genes.大肠杆菌O111 O抗原基因簇的测序及O111特异性基因的鉴定。
J Clin Microbiol. 1998 Nov;36(11):3182-7. doi: 10.1128/JCM.36.11.3182-3187.1998.
7
Identification and cloning of waaF (rfaF) from Bordetella pertussis and use to generate mutants of Bordetella spp. with deep rough lipopolysaccharide.从百日咳博德特氏菌中鉴定并克隆 waaF（rfaF），并用于构建具有深度粗糙型脂多糖的博德特氏菌属突变体。
J Bacteriol. 1998 Jan;180(1):35-40. doi: 10.1128/JB.180.1.35-40.1998.
8
Analysis of the complete DNA sequence of murine cytomegalovirus.小鼠巨细胞病毒全DNA序列分析
J Virol. 1996 Dec;70(12):8833-49. doi: 10.1128/JVI.70.12.8833-8849.1996.
9
The dcr gene family of Desulfovibrio: implications from the sequence of dcrH and phylogenetic comparison with other mcp genes.脱硫弧菌的dcr基因家族：基于dcrH序列及与其他mcp基因的系统发育比较的启示
Antonie Van Leeuwenhoek. 1996 Jul;70(1):21-9. doi: 10.1007/BF00393566.
10
Organization of the Escherichia coli K-12 gene cluster responsible for production of the extracellular polysaccharide colanic acid.负责胞外多糖柯烷酸产生的大肠杆菌K-12基因簇的组织。
J Bacteriol. 1996 Aug;178(16):4885-93. doi: 10.1128/jb.178.16.4885-4893.1996.

本文引用的文献

1
A computer program to search for tRNA genes.一个用于搜索转运RNA基因的计算机程序。
Nucleic Acids Res. 1980 Feb 25;8(4):817-25.
2
A possible novel interaction between the 3'-end of 18 S ribosomal RNA and the 5'-leader sequence of many eukaryotic messenger RNAs.18 S核糖体RNA的3'端与许多真核生物信使RNA的5'前导序列之间可能存在一种新型相互作用。
FEBS Lett. 1982 Oct 18;147(2):133-6. doi: 10.1016/0014-5793(82)81026-0.
3
Recognition of protein coding regions in DNA sequences.DNA序列中蛋白质编码区域的识别。
Nucleic Acids Res. 1982 Sep 11;10(17):5303-18. doi: 10.1093/nar/10.17.5303.
4
Automation of the computer handling of gel reading data produced by the shotgun method of DNA sequencing.DNA测序鸟枪法产生的凝胶读数数据的计算机处理自动化。
Nucleic Acids Res. 1982 Aug 11;10(15):4731-51. doi: 10.1093/nar/10.15.4731.
5
An interactive graphics program for comparing and aligning nucleic acid and amino acid sequences.一个用于比较和比对核酸及氨基酸序列的交互式图形程序。
Nucleic Acids Res. 1982 May 11;10(9):2951-61. doi: 10.1093/nar/10.9.2951.
6
A catalogue of splice junction sequences.剪接连接序列目录。
Nucleic Acids Res. 1982 Jan 22;10(2):459-72. doi: 10.1093/nar/10.2.459.
7
Codon preference and its use in identifying protein coding regions in long DNA sequences.密码子偏好性及其在长DNA序列中识别蛋白质编码区的应用。
Nucleic Acids Res. 1982 Jan 11;10(1):141-56. doi: 10.1093/nar/10.1.141.
8
Use of the 'Perceptron' algorithm to distinguish translational initiation sites in E. coli.使用“感知器”算法区分大肠杆菌中的翻译起始位点。
Nucleic Acids Res. 1982 May 11;10(9):2997-3011. doi: 10.1093/nar/10.9.2997.
9
Method to determine the reading frame of a protein from the purine/pyrimidine genome sequence and its possible evolutionary justification.从嘌呤/嘧啶基因组序列确定蛋白质阅读框的方法及其可能的进化依据。
Proc Natl Acad Sci U S A. 1981 Mar;78(3):1596-600. doi: 10.1073/pnas.78.3.1596.
10
DNA sequences mediating class switching in alpha-immunoglobulins.介导α-免疫球蛋白类别转换的DNA序列。
Science. 1980 Sep 19;209(4463):1360-5. doi: 10.1126/science.6774415.

用于确定核酸序列功能的图解方法。

Graphic methods to determine the function of nucleic acid sequences.

作者信息

Staden R

出版信息

Nucleic Acids Res. 1984 Jan 11;12(1 Pt 2):521-38. doi: 10.1093/nar/12.1part2.521.

DOI:10.1093/nar/12.1part2.521
PMID:6364040
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC321068/
Abstract

We describe an interactive computer program (ANALYSEQ) that is used from a simple graphics terminal. The main purpose of the program is to determine the function of nucleic acid sequences but it also offers the simpler listing, searching and counting options. It contains methods to locate genes by looking for the effects that coding for a protein has on the coding sequence, to locate tRNA genes by looking for secondary structure and conserved bases, and methods to locate signals such as promoters. Techniques to identify unusual regions of sequence and to search for potential Z DNA-forming regions are also included. Most of the routines produce graphical output which gives ease of interpretation and allows superposition of several independent forms of analysis.

摘要

我们描述了一个可从简单图形终端使用的交互式计算机程序（ANALYSEQ）。该程序的主要目的是确定核酸序列的功能，但它也提供了更简单的列表、搜索和计数选项。它包含通过寻找蛋白质编码对编码序列的影响来定位基因的方法，通过寻找二级结构和保守碱基来定位tRNA基因的方法，以及定位启动子等信号的方法。还包括识别序列异常区域和搜索潜在Z-DNA形成区域的技术。大多数程序会生成图形输出，便于解释，并允许叠加几种独立的分析形式。