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系统性红斑狼疮患者家族中淋巴细胞毒素的研究。

A study of lymphocytotoxins in families of patients with systemic lupus erythematosus.

作者信息

Hazelton R A

出版信息

Ann Rheum Dis. 1984 Apr;43(2):136-9. doi: 10.1136/ard.43.2.136.

Abstract

Lymphocytotoxic antibodies are a common feature in the sera of patients with systemic lupus erythematosus. This family study, however, has not confirmed the previous findings of an increased incidence in the sera of their relatives. Adsorption studies suggest that when lymphocytotoxins occur in the sera of normal subjects and relatives of patients they have a different specificity and thus significance.

摘要

淋巴细胞毒性抗体是系统性红斑狼疮患者血清中的常见特征。然而,这项家族研究并未证实之前关于其亲属血清中该抗体发生率增加的发现。吸附研究表明,当淋巴细胞毒素出现在正常受试者和患者亲属的血清中时,它们具有不同的特异性,因而意义也不同。

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Cytotoxins in disease. Autocytotoxins in lupus.疾病中的细胞毒素。狼疮中的自身细胞毒素。
N Engl J Med. 1970 Oct 1;283(14):724-8. doi: 10.1056/NEJM197010012831403.
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Antigens of the Ii system on lymphocytes.
Nat New Biol. 1971 Jun 2;231(22):148-9. doi: 10.1038/newbio231148a0.
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Lymphocytotoxic antibodies in SLE patients and their relatives.
Arthritis Rheum. 1976 Jul-Aug;19(4):700-4. doi: 10.1002/1529-0131(197607/08)19:4<700::aid-art1780190407>3.0.co;2-s.
9
Family distribution of lymphocytotoxins in Hodgkin's disease.
Ann Intern Med. 1976 Feb;84(2):151-6. doi: 10.7326/0003-4819-84-2-151.

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