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1966 - 1983年剑桥透析与移植中心的乙型肝炎

Hepatitis B in the Cambridge dialysis and transplant unit 1966-1983.

作者信息

Nagington J, Sutehall G M, Cohen B J

出版信息

J Med Virol. 1984;13(3):313-20. doi: 10.1002/jmv.1890130313.

DOI:10.1002/jmv.1890130313
PMID:6374034
Abstract

The results of hepatitis B surveillance of the Cambridge dialysis and transplant units from June 1969 to July 1983 are reported. On admission 34/528 (6.44%) haemodialysis patients had anti-HBc. Preadmission screening excluded 19 HBs Ag carrier patients and two carrier staff. Eight patients became antigenaemic after admission and two others were found to be antigenaemic post-transplantation but pretransplant sera were not available from them. These two had active hepatitis and of the others, seven had asymptomatic carriage and one had acute hepatitis during haemodialysis. Two infected patients were admitted temporarily and one antigenaemic organ donor identified retrospectively. No cross infection occurred on the unit and the only instance of accidental infection of a member of staff was from an outpatient.

摘要

报告了1969年6月至1983年7月剑桥透析和移植单位的乙肝监测结果。入院时,528名血液透析患者中有34名(6.44%)抗-HBc阳性。入院前筛查排除了19名HBs Ag携带者患者和2名携带者工作人员。8名患者入院后出现抗原血症,另外2名患者在移植后被发现抗原血症,但无法获得他们移植前的血清。这两名患者患有活动性肝炎,其他患者中,7名无症状携带,1名在血液透析期间患急性肝炎。两名感染患者被临时收治,一名抗原血症器官供体经回顾性鉴定。该单位未发生交叉感染,工作人员意外感染的唯一一例是来自一名门诊患者。

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