人血清中Bay n 7133的高压液相色谱测定法
High-pressure liquid chromatographic assay of Bay n 7133 in human serum.
作者信息
Fasching C E, Hughes C E, Hector R F, Peterson L R
出版信息
Antimicrob Agents Chemother. 1984 May;25(5):596-8. doi: 10.1128/AAC.25.5.596.
Abstract
A high-pressure liquid chromatographic method that includes a Sep-Pak (Waters Associates, Inc., Milford , Mass.) preparation of human serum was employed for the quantitative assay of Bay n 7133. Drug levels of 0.1 to 20 micrograms/ml could be detected. No interference from amphotericin B was found in the chromatographic analysis of Bay n 7133.
摘要
采用一种高压液相色谱法，该方法包括用人血清进行Sep - Pak（ Waters Associates公司，马萨诸塞州米尔福德）预处理，用于定量测定Bay n 7133。可检测到0.1至20微克/毫升的药物水平。在Bay n 7133的色谱分析中未发现两性霉素B的干扰。
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