Maher J W, Hollenbeck J I, Woodward E R
Ann Surg. 1978 Mar;187(3):227-30. doi: 10.1097/00000658-197803000-00001.
Surgical therapy for reflux esophagitis remains controversial. Sixty-five patients who underwent posterior gastropexy between November, 1970 and February, 1976 are presented. Indications for surgery were: esophagitis, 43 patients; esophagitis with stricture, 12 patients; paraesophageal hernia seven patients; incapacitating postfundoplication syndrome, three patients. The average follow-up was 15.6 months. Eighty-two per cent of the patients had a good to excellent result. Twenty-three per cent of the patients developed radiographically recurrent hiatus hernia; however, the incidence of recurrent esophagitis was only nine per cent. Two patients developed postoperative strictures (one de novo, one recurrent). Two patients ultimately required a fundoplication for control of their esophagitis; one patient required a Thal-Nissen procedure. Lower esophageal sphincter pressure on patients with satisfactory results increased from 6.3 +/- 1.3 cm H2O SEM preoperatively, to 17.4 +/- 3.0 cm H2O SEM postoperatively. This increase achieved a statistical significance of p less than 0.001. In patients who had an unsatisfactory result, postoperative sphincter pressures were unchanged from preoperative values. All unsatisfactory results were obtained in patients with complicated esophagitis, i.e., Barrett's ulcer or stricture, alkaline esophagitis, or previous hiatal surgery. Posterior gastropexy appears to constitute effective therapy in the treatment of uncomplicated reflux esophagitis and paraesophageal hiatus hernia without the distressing morbidity associated with the postfundoplication syndrome.
反流性食管炎的手术治疗仍存在争议。本文报告了1970年11月至1976年2月期间接受胃后固定术的65例患者。手术指征为:食管炎43例;食管炎伴狭窄12例;食管旁疝7例;胃底折叠术后综合征导致功能丧失3例。平均随访时间为15.6个月。82%的患者效果良好至极佳。23%的患者经影像学检查发现复发性食管裂孔疝;然而,复发性食管炎的发生率仅为9%。2例患者术后出现狭窄(1例为原发性,1例为复发性)。2例患者最终需要行胃底折叠术来控制食管炎;1例患者需要行Thal-Nissen手术。效果满意的患者术前食管下括约肌压力为6.3±1.3 cm H2O标准误,术后升至17.4±3.0 cm H2O标准误。这种升高具有统计学意义,p值小于0.001。效果不满意的患者术后括约肌压力与术前值无变化。所有不满意的结果均出现在患有复杂性食管炎的患者中,即巴雷特溃疡或狭窄、碱性食管炎或既往有食管裂孔手术史的患者。胃后固定术似乎是治疗非复杂性反流性食管炎和食管旁裂孔疝的有效方法,且不会出现与胃底折叠术后综合征相关的令人痛苦的并发症。