Abe C, Iwai K, Mikami R, Hosoda Y
Zentralbl Bakteriol Mikrobiol Hyg A. 1984 Apr;256(4):541-7. doi: 10.1016/s0174-3031(84)80032-3.
Isolation of Propionibacterium acnes from biopsied lymph nodes of sarcoidosis patients and from the lymph nodes or other tissues of non-sarcoidosis patients was carried out, carefully avoiding contamination by skin-resident P. acnes. Out of 40 sarcoidosis lymph nodes examined, 31 nodes (77.5%) showed a positive culture of P. acnes, while 38 of 180 (21.1%) non-sarcoidosis tissues revealed positive results, the difference being significant (p less than 0.001). Among non-sarcoidosis tissues, the intra-thoracic lymph nodes demonstrated a positive culture in low percentages, while intra-abdominal lymph nodes indicated no positive culture. The possible role of this microorganism in the etiology of sarcoidosis is discussed.
从结节病患者的活检淋巴结以及非结节病患者的淋巴结或其他组织中分离痤疮丙酸杆菌，操作过程中要小心避免皮肤常驻的痤疮丙酸杆菌污染。在检查的40个结节病淋巴结中，31个淋巴结（77.5%）痤疮丙酸杆菌培养呈阳性，而180个非结节病组织中有38个（21.1%）结果呈阳性，差异具有显著性（p小于0.001）。在非结节病组织中，胸内淋巴结培养呈阳性的比例较低，而腹内淋巴结未显示培养呈阳性。本文讨论了这种微生物在结节病病因学中的可能作用。
