Milne J A, Howie A D, Pack A I
Br J Obstet Gynaecol. 1978 Apr;85(4):260-3. doi: 10.1111/j.1471-0528.1978.tb10497.x.
The incidence, severity and time-course of dyspnoea were assessed in 62 women on eight occasions throughout a normal pregnancy. Fifteen per cent of subjects noticed an increase in dyspnoea in the first trimester compared with the nonpregnant state and in almost half of them dyspnoea was experienced before 19 weeks gestation; 76% complained of this symptom by 31 weeks gestation. After this time, few subjects noticed any increase in their symptoms.
在62名女性整个正常孕期的八个不同时间点,对她们呼吸困难的发生率、严重程度和病程进行了评估。与非孕期相比,15%的受试者在孕早期感觉到呼吸困难有所增加,其中近一半在妊娠19周前就出现了呼吸困难;到妊娠31周时,76%的受试者出现了这一症状。在此之后,很少有受试者注意到症状有任何加重。