Gorsky M, Silverman S
J Prosthet Dent. 1984 Aug;52(2):164-6. doi: 10.1016/0022-3913(84)90088-x.
Four hundred patients with oral cancer were studied to determine if there appeared to be a risk related to denture wearing. Forty-three percent of the group wore dentures, and there seemed to be no correlation between the wearing of dentures and any specific cancer site. Furthermore, there was no difference between denture and nondenture wearers relative to age, sex, time from first signs or symptoms to diagnosis, tumor stage, or tobacco use. In addition, a large number of individuals in the general population wear dentures, and carcinomas occur infrequently in denture-bearing sites. Other studies have shown no difference between denture wearers and control groups in the occurrence of oral cancer. Therefore, it does not seem plausable at this time to consider denture irritation as a significant carcinogenic aggravating factor.
对400例口腔癌患者进行了研究，以确定佩戴假牙是否存在相关风险。该组中有43%的患者佩戴假牙，假牙佩戴与任何特定癌症部位之间似乎没有相关性。此外，在年龄、性别、从首次出现症状到诊断的时间、肿瘤分期或吸烟情况方面，戴假牙者与不戴假牙者之间没有差异。此外，普通人群中有大量个体佩戴假牙，而在有假牙的部位很少发生癌症。其他研究表明，戴假牙者与对照组在口腔癌的发生方面没有差异。因此，目前将假牙刺激视为一个重要的致癌加重因素似乎不太合理。
