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前列腺素F2α在妊娠大鼠体内的分布

Prostaglandin F2alpha distribution in pregnant rats.

作者信息

Persaud T V

出版信息

Exp Pathol (Jena). 1978;15(1):46-8. doi: 10.1016/s0014-4908(78)80088-x.

DOI:10.1016/s0014-4908(78)80088-x
PMID:639925
Abstract

Studies on the placental transfer and distribution of 3H-PGF2alpha in rats on day 14 of gestation revealed that the isotope and/or its metabolites readily crossed the placenta. Notable levels of radioactivity were present in the embryos as well as in the placentas. The highest concentration of radioactivity was detected in the amniotic fluid. Maternal liver, kidney, and gut also showed significant uptake of the isotope.

摘要

对妊娠第14天大鼠胎盘转运和分布3H-PGF2α的研究表明，该同位素及其代谢产物很容易穿过胎盘。胚胎和胎盘中均存在显著水平的放射性。羊水中检测到最高浓度的放射性。母体的肝脏、肾脏和肠道也显示出对该同位素的显著摄取。

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