前列腺素敏感腺苷酸环化酶在人上消化道中的分布。
Distribution of prostaglandin-sensitive adenylate cyclase in human upper gastrointestinal tract.
作者信息
Simon B, Kather H
出版信息
Digestion. 1978;17(3):264-7. doi: 10.1159/000198116.
PMID:640274
Abstract
The localization of the prostaglandin-sensitive adenylate cyclase in the upper gastrointestinal tract in human beings was studied. The prostaglandin-sensitive enzyme was almost evenly distributed throughout the fundic, antral and duodenal mucosa. The enhancement of enzyme activity in the presence of maximally effective prostaglandin concentrations exceeded basal levels by about 200%. The physiological role of the prostaglandin sensitive adenylate cyclase in gastric and duodenal function, however, remains to be established.
摘要
对人类上消化道中前列腺素敏感的腺苷酸环化酶的定位进行了研究。前列腺素敏感酶几乎均匀地分布于整个胃底、胃窦和十二指肠黏膜。在最大有效前列腺素浓度存在的情况下，酶活性的增强超过基础水平约200%。然而，前列腺素敏感腺苷酸环化酶在胃和十二指肠功能中的生理作用仍有待确定。
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