变形链球菌不溶性葡聚糖对巨噬细胞前列腺素E2和血栓素B2分泌的刺激作用。
The stimulation of macrophage prostaglandin E2 and thromboxane B2 secretion by Streptococcus mutans insoluble glucans.
作者信息
Abiko Y, Shibata Y, Fukushima K, Murai S, Takiguchi H
出版信息
FEBS Lett. 1983 Apr 18;154(2):297-300. doi: 10.1016/0014-5793(83)80170-7.
PMID:6403385
Abstract
The effect of insoluble glucan synthesized by Streptococcus mutans on [3H]arachidonate metabolites secretion from peritoneal macrophages was studied. Insoluble glucans stimulated [3H]arachidonate release and secretion of prostaglandin E2 and thromboxane B2 from macrophages. In contrast, commercial soluble glucan (dextran) did not induce [3H]arachidonate release.
摘要
研究了变形链球菌合成的不溶性葡聚糖对腹膜巨噬细胞分泌[3H]花生四烯酸代谢物的影响。不溶性葡聚糖刺激巨噬细胞释放[3H]花生四烯酸以及分泌前列腺素E2和血栓素B2。相比之下，市售的可溶性葡聚糖（右旋糖酐）未诱导[3H]花生四烯酸释放。
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