一项关于人类肺炎支原体感染中特异性IgM抗体反应的研究。
A study of the specific IgM antibody response in Mycoplasma pneumoniae infection in man.
作者信息
Chamberlain P, Saeed A A
出版信息
J Hyg (Lond). 1983 Apr;90(2):207-11. doi: 10.1017/s0022172400028874.
Abstract
Sera from 96 patients with Mycoplasma pneumoniae infection were examined for specific IgM antibody. The complement fixation test was used to measure the IgM after separation by ultracentrifugation through sucrose density gradients. Of patients under the age of 20 years 78% displayed positive specific IgM titres. In older patients only 34% were IgM positive. The specific IgM remained detectable, but at decreasing levels, during the follow-up period of 5 months. This diagnostic technique appears to be of value in children and young adults experiencing primary infection with M. pneumoniae.
摘要
对96例肺炎支原体感染患者的血清进行了特异性IgM抗体检测。采用补体结合试验，通过蔗糖密度梯度超速离心分离后测定IgM。20岁以下的患者中，78%的特异性IgM滴度呈阳性。年龄较大的患者中只有34%的IgM呈阳性。在5个月的随访期内，特异性IgM仍可检测到，但水平逐渐下降。这种诊断技术对于初次感染肺炎支原体的儿童和年轻人似乎具有重要价值。
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