Lynch W C, Libby L, Johnson H F
Psychopharmacology (Berl). 1983;79(4):370-1. doi: 10.1007/BF00433421.
Aggression and thermal pain thresholds were measured in separate groups of isolated male mice following 0.2-5.0 mg/kg SC injections of the opiate antagonist naloxone. The drug inhibited aggressive behaviors dose-dependently, but had no effect on pain. These results suggest that endogenous opioid systems may be activated during repeated intermale aggressive encounters.
在单独的雄性隔离小鼠组中，皮下注射0.2 - 5.0毫克/千克的阿片类拮抗剂纳洛酮后，测量其攻击阈值和热痛阈值。该药物剂量依赖性地抑制攻击行为，但对疼痛没有影响。这些结果表明，内源性阿片系统可能在反复的雄性间攻击遭遇中被激活。
