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运动诱发性哮喘患儿训练后的改善情况。

Improvement after training of children with exercise-induced asthma.

作者信息

Svenonius E, Kautto R, Arborelius M

出版信息

Acta Paediatr Scand. 1983 Jan;72(1):23-30. doi: 10.1111/j.1651-2227.1983.tb09658.x.

Abstract

Fifty children with exercise-induced asthma (EIA) volunteered to take part in a study of the influence of training on EIA. 1) Ten children did not change physical activity. 2) Twelve children trained after premedication with salbutamol inhalations. 3) Thirteen children trained after premedication with disodium chromoglicate (DSCG) and used that drug for treatment. 4) Fifteen children trained in their own regimen, commonly after premedication with salbutamol. Their training programme (groups 2-3) consisted of high load exercise periods of two minutes interrupted by intervals of rest for two minutes during 30 minutes followed by interval swimming for another 30 minutes, twice a week for 3-4 months. Before the training period the degree of EIA was tested with a battery of lung function tests before and after running for 6 minutes on a treadmill at heart rate 170. EIA after training was measured applying the same procedure. Cardiocirculatory performance was evaluated before and after training with work on a cycle ergometer and expressed as W/kg body weight at heart rate 170. The children in groups 2, 3 and 4 improved their physical working capacity by 11% (p less than 0.01), 21% and 11%, respectively, but no improvement was found in group 1. Significant improvements in EIA after the training periods were found in all training groups, but basal asthma improved most in group 3, probably due to the basal treatment with DSCG.

摘要

五十名运动诱发性哮喘(EIA)患儿自愿参与一项关于训练对EIA影响的研究。1)十名儿童未改变体育活动量。2)十二名儿童在吸入沙丁胺醇进行预处理后进行训练。3)十三名儿童在吸入色甘酸钠(DSCG)预处理后进行训练,并使用该药物进行治疗。4)十五名儿童按照自己的方案进行训练,通常在吸入沙丁胺醇预处理后。他们的训练计划(第2 - 3组)包括30分钟内两分钟的高负荷运动时段,中间间隔两分钟休息,随后再进行30分钟的间歇游泳,每周两次,持续3 - 4个月。在训练期之前,通过一系列肺功能测试在跑步机上以心率170跑步6分钟前后对EIA程度进行测试。训练后的EIA采用相同程序进行测量。通过在自行车测力计上运动来评估训练前后的心血管功能,并以心率170时的W/kg体重表示。第2、3和4组的儿童分别将其身体工作能力提高了11%(p < 0.01)、21%和11%,但第1组未发现改善。在所有训练组中训练期后EIA均有显著改善,但基础哮喘在第3组改善最为明显,可能是由于使用DSCG进行基础治疗。

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