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子宫内膜癌的特征及其内分泌相关性

Profiles and endocrine correlations in endometrial carcinoma.

作者信息

Falsetti L, Omodei U, Dordoni D, Scagliola P, Turla R, Zotti L, Archetti L

出版信息

Eur J Gynaecol Oncol. 1983;4(1):30-4.

PMID:6407836
Abstract

The Authors compared the mean LH, FSH, PRL, E1, E2, Testosterone, Androstenedione plasmatic levels in a group of post-menopausal women affected by endometrial carcinoma (EK), with those of a control group presenting clinical characteristics as close as possible to those of the pathologic group. The case series was significant. They found no significant difference between the two groups' hormonal levels. On the other hand, E1 levels were found to increase along-side with obesity. In patients affected by EK, E1 plasma levels significantly increased alongside with the post-menopausal age. Conversely, in the control group, this hormonal value significantly and progressively decreased from the menopause onwards. Furthermore, the Authors studied the effects of surgical intervention on the hormonal picture in EK bearers.

摘要

作者比较了一组患有子宫内膜癌(EK)的绝经后女性的血浆促黄体生成素(LH)、促卵泡生成素(FSH)、催乳素(PRL)、雌酮(E1)、雌二醇(E2)、睾酮、雄烯二酮水平,与一组临床特征尽可能与病理组接近的对照组的相应水平。病例系列具有统计学意义。他们发现两组激素水平之间没有显著差异。另一方面,发现E1水平随着肥胖程度增加。在患有EK的患者中,E1血浆水平随着绝经后年龄显著升高。相反,在对照组中,从绝经后开始,该激素值显著且逐渐下降。此外,作者研究了手术干预对EK患者激素情况的影响。

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