淋病奈瑟菌：自然传播后分型标志物的稳定性
Neisseria gonorrhoeae: stability of typing markers after natural transmission.
作者信息
Copley C G, Chiswell C P, Egglestone S I
出版信息
Br J Vener Dis. 1983 Aug;59(4):237-41. doi: 10.1136/sti.59.4.237.
Abstract
The gonococcal isolates from 15 contact pairs and three large contact groups were examined using various methods to assess the stability of different typing markers. With the exception of one contact group which showed variable proline requirements, the auxotypes were stable during natural transmission. Serogrouping using the coagglutination method to detect W and M antigens was undertaken. The lipopolysaccharide M antigens were readily lost and gained during transmission whereas the protein W antigens represented stable markers and are thus useful for epidemiological studies.
摘要
使用多种方法对来自15对接触者和三个大型接触群体的淋球菌分离株进行检测，以评估不同分型标志物的稳定性。除了一个接触群体显示出可变的脯氨酸需求外，在自然传播过程中，营养型是稳定的。采用协同凝集法检测W和M抗原进行血清分型。脂多糖M抗原在传播过程中很容易丢失和获得，而蛋白质W抗原是稳定的标志物，因此可用于流行病学研究。
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