血小板激活因子刺激人血小板中的磷脂酰肌醇周转。
Platelet-activating factor stimulates phosphatidylinositol turnover in human platelets.
作者信息
MacIntyre D E, Pollock W K
出版信息
Biochem J. 1983 May 15;212(2):433-7. doi: 10.1042/bj2120433.
Abstract
Platelet-activating factor stimulates phosphatidylinositol turnover in human platelets as indicated by [32P]phosphatidate accumulation in platelets pre-labelled with [32P]Pi, and by [3H]phosphatidate accumulation and [3H]phosphatidylinositol loss in platelets pre-labelled with [3H]arachidonate. These effects of platelet-activating factor are direct and are independent of the production and/or release of endogenous platelet agonists such as ADP, 5-hydroxytryptamine and thromboxane A2.
摘要
血小板活化因子可刺激人血小板中的磷脂酰肌醇周转，这表现为用[32P]Pi预标记的血小板中[32P]磷脂酸的积累，以及用[3H]花生四烯酸预标记的血小板中[3H]磷脂酸的积累和[3H]磷脂酰肌醇的损失。血小板活化因子的这些作用是直接的，且独立于内源性血小板激动剂如ADP、5-羟色胺和血栓素A2的产生和/或释放。
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本文引用的文献
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2
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