Mair T S
Bell Equine Veterinary Clinic, Mereworth, Maidstone, Kent.
Vet Rec. 1996 Jan 27;138(4):89-91. doi: 10.1136/vr.138.4.89.
The clinical features of 18 cases of summer pasture associated obstructive pulmonary disease were reviewed. The horses had signs of obstructive pulmonary disease (expiratory dyspnoea, wheezing and crackling lung sounds and coughing) during the spring, summer or autumn while they were kept permanently at grass with no access to hay or straw, for at least two consecutive years. In nine cases there was a seasonal incidence with the disease occurring during April and May. Eleven of the horses were affected by bouts of severe dyspnoea. Eleven of the horses also suffered from chronic obstructive pulmonary disease and two were affected by idiopathic headshaking. Endoscopy revealed evidence of lower airway inflammation, and a cytological examination of tracheal aspirates and bronchoalveolar lavage fluid revealed a neutrophilia. Moving the horses into a stable controlled the clinical disease effectively in only two of the 16 cases. Oral clenbuterol was effective in only seven of 15 cases. Systemic dexamethasone or oral prednisolone, in combination with clenbuterol, was the most effective treatment.
回顾了18例夏季牧场相关阻塞性肺病病例的临床特征。这些马匹在春季、夏季或秋季出现阻塞性肺病症状(呼气性呼吸困难、喘息、肺部啰音和咳嗽),它们连续至少两年一直以青草为食,无法获取干草或稻草。9例有季节性发病情况,疾病发生在4月和5月。11匹马受到严重呼吸困难发作的影响。11匹马还患有慢性阻塞性肺病,2匹受特发性摇头症影响。内窥镜检查显示下呼吸道有炎症迹象,气管吸出物和支气管肺泡灌洗 fluid的细胞学检查显示中性粒细胞增多。将马匹转移到马厩仅在16例中的2例有效控制了临床疾病。口服克伦特罗仅在15例中的7例有效。全身性地塞米松或口服泼尼松龙与克伦特罗联合使用是最有效的治疗方法。 (注:原文中“bronchoalveolar lavage fluid”翻译时少了一个单词,正确完整的翻译应该是“支气管肺泡灌洗液体” )