Lundar T, Frøysaker T, Nornes H, Lilleaasen P
Scand J Thorac Cardiovasc Surg. 1983;17(2):149-55. doi: 10.3109/14017438309109880.
Brain damage following open-heart surgery is receiving increasing attention. Efforts are being made to improve the setting for cardiac surgery so as to avoid such complications. When they occur, their recognition is retrospective, when the cerebral lesion is inevitable. Because heavy sedation is necessary, clinical supervision with respect to brain function is both difficult and unreliable in the early postoperative period. We therefore submitted 34 selected patients to neurosurgical intensive care supervision. The measures included postoperative monitoring of intracranial epidural pressure (EDP), of arterial blood pressure (BP) and of central venous pressure (CVP). In 25 patients there was rise in EDP during the first postoperative hours. Six of these patients received mannitol treatment and in three of them barbiturate was additionally given, in order to reduce EDP and improve the cerebral perfusion pressure (CPP = BP-EDP). Nevertheless EDP progressed to brain tamponade six days postoperatively in one case. In patients with raised EDP, weaning from the ventilator should be postponed until EDP has almost normalized. The EDP recording is a valuable guide in the postoperative management of the individual patient.
心脏直视手术后的脑损伤正受到越来越多的关注。人们正在努力改善心脏手术的环境,以避免此类并发症。当并发症发生时,由于脑损伤不可避免,其识别是回顾性的。由于需要深度镇静,术后早期对脑功能的临床监测既困难又不可靠。因此,我们对34例选定的患者进行了神经外科重症监护。措施包括术后监测颅内硬膜外压力(EDP)、动脉血压(BP)和中心静脉压(CVP)。25例患者术后最初数小时内EDP升高。其中6例患者接受了甘露醇治疗,3例额外给予了巴比妥类药物,以降低EDP并改善脑灌注压(CPP = BP - EDP)。然而,有1例患者术后6天EDP进展为脑压塞。对于EDP升高的患者,应推迟撤机,直到EDP几乎恢复正常。EDP记录对个体患者的术后管理是一个有价值的指导。