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对白假丝酵母菌的免疫反应。III. 淋巴细胞或血清的被动转移对小鼠念珠菌病的影响。

Immunologic responses to Candida albicans. III. Effects of passive transfer of lymphoid cells or serum on murine candidiasis.

作者信息

Pearsall N N, Adams B L, Bunni R

出版信息

J Immunol. 1978 Apr;120(4):1176-80.

PMID:641343
Abstract

Passive transfer of immune serum gave a significant degree of protection against deep seated candidiasis in mice. Repeated attempts to transfer resistance by the transfer of sensitized lymphoid cells gave negative results, even though cutaneous delayed hypersensitivity was transferred by the cells. The results suggest that cell-mediated immunity is not of primary importance in this model of murine candidiasis, and that humoral immunity contributes to protection.

摘要

免疫血清的被动转移给予小鼠针对深部念珠菌病显著程度的保护。尽管致敏淋巴细胞能够转移皮肤迟发型超敏反应,但通过转移致敏淋巴细胞来转移抗性的多次尝试均得到阴性结果。结果表明,在这种小鼠念珠菌病模型中,细胞介导的免疫并非至关重要,而体液免疫有助于提供保护。

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J Immunol. 1978 Apr;120(4):1176-80.
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