Leakey J E, Althaus Z R, Bailey J R, Slikker W
Biochem J. 1983 Sep 15;214(3):1007-9. doi: 10.1042/bj2141007.
UDP-glucuronyltransferase was assayed in liver from adult rhesus monkeys and foetuses during late gestation. Activities toward 2-aminophenol, 5-hydroxytryptamine, 1-naphthol and 4-nitrophenol in the foetal liver ranged from 46 to 114% of adult values, whereas activities toward bilirubin, oestradiol and testosterone were less than 5% of adult values. This suggests that in primates UDP-glucuronyltransferase develops differentially in two clusters analogous to that in the rat.
在成年恒河猴以及妊娠晚期胎儿的肝脏中对尿苷二磷酸葡萄糖醛酸基转移酶进行了测定。胎儿肝脏中针对2-氨基酚、5-羟色胺、1-萘酚和4-硝基酚的活性为成年值的46%至114%，而针对胆红素、雌二醇和睾酮的活性则低于成年值的5%。这表明在灵长类动物中，尿苷二磷酸葡萄糖醛酸基转移酶在两个类似于大鼠的簇中差异发育。
