Ewusi-Mensah I, Saunders J B, Wodak A D, Murray R M, Williams R
Br Med J (Clin Res Ed). 1983 Nov 12;287(6403):1417-9. doi: 10.1136/bmj.287.6403.1417.
Seventy one patients with alcoholic liver disease and an equal number with non-alcoholic liver disease were interviewed using the schedule for affective disorders and schizophrenia. Forty seven (66%) of the group with alcoholic liver disease had or had had psychiatric illnesses compared with 23 (32%) of the control group (p less than 0.001). Affective disorder, particularly major depression, neurotic disorders, and antisocial personality, were all more common among the patients with alcoholic liver disease than the controls. No patient had schizophrenia or other forms of psychosis. Among the patients with alcoholic liver disease 11 men (24%) and 14 women (54%) had an affective or a neurotic disorder that had antedated their heavy drinking, and 30 (77%) of those who had had such a problem at any time had symptoms at the time of interview. Abstinence from alcohol is essential for patients with severe alcoholic liver disease. In view of the high prevalence of psychiatric disorders in these patients psychiatric assessment is important to increase the patients' likelihood of complying with such advice.
使用情感障碍和精神分裂症检查表对71例酒精性肝病患者以及同等数量的非酒精性肝病患者进行了访谈。酒精性肝病组中有47例（66%）曾患有或曾患过精神疾病，而对照组为23例（32%）（p<0.001）。情感障碍，尤其是重度抑郁症、神经症和反社会人格，在酒精性肝病患者中比对照组更为常见。没有患者患有精神分裂症或其他形式的精神病。在酒精性肝病患者中，11名男性（24%）和14名女性（54%）患有情感障碍或神经症，且这些疾病早于他们大量饮酒的时间，在任何时候有过此类问题的患者中，30例（77%）在访谈时仍有症状。对于重度酒精性肝病患者，戒酒至关重要。鉴于这些患者中精神障碍的高患病率，进行精神评估对于提高患者遵循此类建议的可能性很重要。
