Andreasen N C, Grove W M, Shapiro R W, Keller M B, Hirschfeld R M, McDonald-Scott P
Arch Gen Psychiatry. 1981 Apr;38(4):400-5. doi: 10.1001/archpsyc.1981.01780290034003.
It is important to determine the reliability of lifetime diagnosis in a nonpatient population, for this type of diagnostic data and this type of sample are used in many genetic, epidemiological, and nosological studies. We examined the reliability of lifetime diagnosis when the Schedule for Affective Disorders and Schizophrenia-Lifetime Version and Research Diagnostic Criteria were used to interview ill and well relatives of probands in the National Institute of Mental Health Collaborative Study of the Psychobiology of Depression. Subjects were interviewed three times, so data are available concerning both short- and long-interval test-retest reliability. Short-interval test-retest reliability was excellent for both diagnoses and symptoms. Reliability was also quite high in the long-interval test-retest study. We conclude that it is possible to make lifetime diagnoses reliably in a nonpatient population.
确定非患者群体中终生诊断的可靠性很重要，因为许多基因、流行病学和疾病分类学研究都使用这类诊断数据和这类样本。在国立精神卫生研究所抑郁症心理生物学合作研究中，我们使用情感障碍和精神分裂症日程表-终生版及研究诊断标准对先证者的患病和未患病亲属进行访谈，以此检验终生诊断的可靠性。对受试者进行了三次访谈，因此可获得关于短期和长期重测信度的数据。短期重测信度在诊断和症状方面都非常出色。在长期重测研究中，信度也相当高。我们得出结论，在非患者群体中进行可靠的终生诊断是可能的。
