丙磺舒的新型分光光度荧光测定法。
New spectrophotofluorometric assay for probenecid.
作者信息
Cunningham R F, Israili Z H, Dayton P G
出版信息
J Pharm Sci. 1978 Mar;67(3):434-6. doi: 10.1002/jps.2600670351.
PMID:641745
Abstract
A new spectrophotofluorometric assay for probenecid is presented based on conversion of the drug to a fluorescent anthranilic acid derivative. The assay is especially applicable with "clean" biological fluids such as cerebrospinal fluid and offers severalfold greater sensitivity than the commonly used UV method.
摘要
本文介绍了一种新的丙磺舒分光光度荧光测定法，该方法基于将药物转化为荧光邻氨基苯甲酸衍生物。该测定法特别适用于“纯净”的生物流体，如脑脊液，并且比常用的紫外法灵敏度高几倍。
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