Wagner G, Bohr L, Wagner P, Petersen L N
Am J Obstet Gynecol. 1984 Jan 15;148(2):147-50. doi: 10.1016/s0002-9378(84)80165-9.
Vaginal oxygen and carbon dioxide tensions were measured continuously in a group of normal young women on the second day of menstruation during a 90-minute period. PO2 averaged 3 mm Hg (+/- 11 SD) and PCO2 averaged 64 mm Hg (+/- 13 SD). The value rose to that of atmospheric air when a tampon was inserted and gradually fell, giving a mean value of 112 mm Hg (+/- 18 SD) during the following 90 minutes; preinsertion values were reached in about 8 hours. Carbon dioxide rose rapidly to almost preinsertion values (mean value of 50 mm Hg +/- 12 SD) during the 90-minute period and remained steady at this level during extended periods. As in vitro studies have indicated an oxygen-dependent production of a toxin-like protein from Staphylococcus aureus, it is suggested that intravaginal tampons may be a risk factor in the development of toxic shock syndrome by supplying oxygen, thus changing the vaginal microenvironment from anaerobic to aerobic.
在月经周期的第二天，对一组正常年轻女性在90分钟内连续测量阴道内的氧分压和二氧化碳分压。氧分压平均为3毫米汞柱（±11标准差），二氧化碳分压平均为64毫米汞柱（±13标准差）。当插入卫生棉条时，该值升至大气空气的值，并逐渐下降，在接下来的90分钟内平均值为112毫米汞柱（±18标准差）；约8小时后达到插入前的值。在90分钟内，二氧化碳迅速上升至几乎插入前的值（平均值为50毫米汞柱±12标准差），并在较长时间内保持稳定。由于体外研究表明金黄色葡萄球菌可产生一种依赖氧气的毒素样蛋白质，因此有人认为，阴道内使用卫生棉条可能是中毒性休克综合征发病的一个危险因素，因为它提供了氧气，从而将阴道微环境从厌氧变为需氧。
