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袋鼠体内夸张的波反射模拟了动脉反搏。

Exaggerated wave reflection in the kangaroo simulates arterial counterpulsation.

作者信息

Avolio A P, Nichols W W, O'Rourke M F

出版信息

Am J Physiol. 1984 Feb;246(2 Pt 2):R267-70. doi: 10.1152/ajpregu.1984.246.2.R267.

Abstract

The ascending aortic pressure wave in kangaroos is quite different from that seen in other experimental animals and in humans, despite an ascending aortic flow wave that is virtually identical. The diastolic pressure surge in the ascending aortic pressure wave of kangaroos is very prominent--so much so that peak diastolic pressure is often greater than peak systolic pressure, with the pressure wave resembling that recorded in humans during intra-aortic balloon counterpulsation. Ascending aortic impedance patterns in kangaroos indicate the presence of a single functionally discrete reflecting site in the peripheral circulation, with high reflection coefficient. All findings--of pulse contour and impedance patterns--are explicable on the basis of arterial anatomy and body shape. Wave reflection from the distant, large, and vascular lower body appears to dominate the effects of wave reflection from the short, small, and less vascular head and forelimb system.

摘要

袋鼠升主动脉压力波与其他实验动物及人类的有很大不同,尽管升主动脉血流波几乎相同。袋鼠升主动脉压力波中的舒张期压力激增非常显著——以至于舒张期峰值压力常常大于收缩期峰值压力,其压力波类似于人类主动脉内球囊反搏时记录到的压力波。袋鼠升主动脉阻抗模式表明外周循环中存在一个功能上离散的单一反射位点,反射系数较高。所有关于脉搏轮廓和阻抗模式的发现都可以根据动脉解剖结构和身体形状来解释。来自遥远、较大且血管丰富的下半身的波反射似乎主导了来自短小、血管较少的头部和前肢系统的波反射的影响。

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