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[前列腺癌的高压治疗]

[High-voltage therapy of prostate cancer].

作者信息

Schnorr D, Kelly L U, Guddat H M, Schubert J, Gorski J, Schorcht J, Mau S, Wehnert J

出版信息

Z Urol Nephrol. 1983 Dec;76(12):753-61.

PMID:6422667
Abstract

High-voltage therapy is becoming increasingly important as a form of individual differential therapy of carcinoma of the prostate. Around 40% of all patients with a diagnosis of carcinoma of the prostate can be treated with high-voltage therapy. The precondition is the absence of bone and soft-tissue metastases and of juxtaregional lymph-node metastases. Individual carcinoma therapy is based on pre-therapeutic tumor classification according to the TNM system. The 5-year survival rates are presented from a retrospective study carried out using primary radiation monotherapy and a combined hormone and radiation therapy; these figures were calculated by the life-table method. The study revealed no significant differences between the two forms of therapy as regards 5-year survival rates. The 5-year survival rates of all patients of the classifications T0-T3Nx-N2M0 irradiated (n: 198) (72% +/- 11% for hormone plus radiation therapy and 74% +/- 11% for radiation monotherapy) did not differ greatly from those of a normal male population of the same age (77%). High-voltage therapy of carcinoma of the prostate can thus be classified as a curative method of treatment.

摘要

作为前列腺癌个体化差异治疗的一种形式,高压疗法正变得越来越重要。在所有被诊断为前列腺癌的患者中,约40%可以接受高压疗法治疗。前提是不存在骨和软组织转移以及区域旁淋巴结转移。个体化癌症治疗基于根据TNM系统进行的治疗前肿瘤分类。5年生存率来自一项回顾性研究,该研究采用了单纯放射治疗和激素与放射联合治疗;这些数据通过寿命表法计算得出。该研究显示,在5年生存率方面,两种治疗形式之间没有显著差异。所有T0 - T3Nx - N2M0分期接受放疗的患者(n:198)(激素加放疗组为72%±11%,单纯放疗组为74%±11%)的5年生存率与同年龄正常男性人群的5年生存率(77%)相比差异不大。因此,前列腺癌的高压疗法可被归类为一种治愈性治疗方法。

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[High-voltage therapy of prostate cancer].[前列腺癌的高压治疗]
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Excellent results from high dose rate brachytherapy and external beam for prostate cancer are not improved by androgen deprivation.高剂量率近距离放射疗法和外照射治疗前列腺癌的卓越疗效不会因雄激素剥夺而得到改善。
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Improved biochemical disease-free survival of men younger than 60 years with prostate cancer treated with high dose conformal external beam radiotherapy.接受高剂量适形外照射放疗的60岁以下前列腺癌男性患者,其生化无病生存率得到改善。
J Urol. 2003 Nov;170(5):1828-32. doi: 10.1097/01.ju.0000093720.46502.24.

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Assessment of the regional lymph node status in radiation monotherapy of prostatic cancer.前列腺癌放射单疗法中区域淋巴结状态的评估
Int Urol Nephrol. 1986;18(1):75-84. doi: 10.1007/BF02082652.