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诊断微生物学中的凝集素

Lectins in diagnostic microbiology.

作者信息

Doyle R, Keller K

出版信息

Eur J Clin Microbiol. 1984 Feb;3(1):4-9. doi: 10.1007/BF02032806.

Abstract

Current literature suggests that lectins are becoming valuable reagents for the laboratory identification of infectious agents. The identification of bacteria, fungi, or protozoa may be confirmed if they bind to or agglutinate with certain lectins. Assay kits utilizing specific lectin agglutination reactions, coupled with conventional enzyme determinations, have been proposed for several bacteria. Factors such as specificity, stability, assay rapidity, and costs combine to make lectins attractive diagnostic reagents. It is likely that the use of lectins in diagnostic microbiology will continue to grow.

摘要

当前文献表明,凝集素正成为实验室鉴定感染因子的重要试剂。如果细菌、真菌或原生动物能与某些凝集素结合或发生凝集反应,那么其鉴定结果便可得到确认。针对多种细菌,已有人提出利用特定凝集素凝集反应并结合传统酶测定的检测试剂盒。特异性、稳定性、检测速度和成本等因素共同作用,使得凝集素成为颇具吸引力的诊断试剂。凝集素在诊断微生物学中的应用很可能会持续增加。

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